HYPERKINETIC BOYS AND THEIR SIBLINGS S YOUNG ADULTS

这是一项多变量年轻成人随访研究的最后阶段， 几个患有多动症/注意力缺陷障碍的男孩样本 (HK/ADD），他们的非多动全兄弟，和非多动 志愿者同学 所有患者最初在6岁至 12例转诊至爱荷华州大学儿童精神病学诊所;全部为 经儿童精神科医生/住院医生诊断为HK/ADD， eitiher双氯芬酸（主要与哌甲酯）或 心理上（主要是短期的父母和/或老师 咨询）;所有这些都由本研究员在 青春期（12-18岁）和/或青年期（21-23岁）。 主要 样本是：a）早期用药组（HK/ADD男孩，诊断为 1967-1972年，平均使用哌醋甲酯治疗3年）; B）a 过渡期药物治疗组（1972-1975年诊断的HK/ADD男孩， 也用哌甲酯治疗）; c）过渡期未用药）组 (HK 1972年至1975年期间也诊断出ADD男孩，但由于医生 偏好，不接受精神药物治疗）;和d）晚期未用药 组（1975- 1978年诊断的HK/ADD男孩，未接受 精神药物）。 截至本补助期结束时，共有421名男孩（160名 接受药物治疗的患者，40例过渡期接受药物治疗的患者，22例过渡期 未用药患者，37例晚期未用药患者，104例兄弟，58例 同学）将在他们21岁生日后的两年内被看到 并进行了一系列多特征和多方法的测试， 问卷调查和访谈。 此外，146宗传票转介个案， 游戏室诊断的男孩和他们的100名正常对照将被随访 年龄在18到20岁之间。 本研究的总体目标是 描述HK/ADD儿童的生命历程，并识别 单独的预测器（例如，攻击性，智商）和环境 预测器（例如，治疗，养育方式）的差异， 当然了 一系列多变量分析的结果将提供一个 详细描述了药物治疗和 未服药的HK/ADD男孩作为青少年和年轻人，与同学和 兄弟姐妹控制。 计划中的比较将测试对这些问题的影响。 运动机能亢进本身的结果;兴奋剂药物治疗的结果;以及 对药物的反应。 建立预测和诊断手段 残留的ADD/成人MBD将是一个特别关注的问题。

This is the final phase of a multivariate young adult follow-up study of several samples of boys with Hyperkinetic/Attention Deficit Disorder (HK/ADD), of their nonhyperkinetic full brothers, and of nonhyperkinetic volunteer classmates. All patients were originally evaluated at ages 6 to 12 as referrals to the University of Iowa child psychiatry clinic; all were diagnosed as HK/ADD by child psychiatry faculty/residents' all were treated eitiher pharmacologically (primarily with methylphenidate) or psychologically (primarily with short-term parent and/or teacher counseling); and all are being followed up by the present investigator at adolescence (ages 12-18) and/or young adulthood (ages 21-23). The main samples are: a) an Early Medicated group (HK/ADD boys diagnosed between 1967-1972 and treated with methylphenidate for an average of 3 years); b) a Transitional Medicated group (HK/ADD boys diagnosed between 1972-1975 and also treated with methylphenidate); c) a Transitional Unmedicated) group (HK/ADD boys also diagnosed between 1972-1975 but, because of physician preference, not treated with psychotropic drugs); and d) a Late Unmedicated group (HK/ADD boys diagnosed between 1975-19788 and not treated with psychotropic drugs). By the end of the present grant period, a total of 421 boys (160 Early Medicated patients, 40 Transitional Medicated patients, 22 Transitional Unmedicated patients, 37 Late Unmedicated patients, 104 brothers, and 58 classmates) will have been seen within two years after their 21st birthday and administered a multitrait and multimethod battery of tests, questionnaires, and interviews. In addition, 146 consecutively-referred, playroom-diagnosed boys and their 100 normal controls will be followed up at between 18 to 20 years of age. The general aim of the present study is to describe the life course of the HK/ADD child and to identify the individual predictors (e.g., aggression, IQ) and the environmental predictors (e.g., treatment, parenting styles) of differences in life course. Results of a series of multivariate analyses will provide a detailed description of a variety of outcomes among both medicated and unmedicated HK/ADD boys as adolescents and young adults, with classmate and sibling controls. Planned comparisons will test the effects on these outcomes of hyperkinesis per se; of stimulant drug treatment; and of response to medication. Establishing means for predicting and diagnosing residual ADD/adult MBD will be a special concern.