VISUAL BEHAVIOR--ANATOMICAL AND FUNCTIONAL BASIS

视觉行为——解剖学和功能基础

• 批准号: 3399208
• 负责人: IRVING T DIAMOND
• 金额: $ 11.26万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1983
• 资助国家: 美国
• 起止时间: 1983-09-01 至 1988-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3399208
• 关键词: behavior test; brain mapping; experimental brain lesion; interhemispheric transfer; learning transfer; memory; neuropsychology; psychophysiology; superior colliculus

The starting point of this proposal is a number of behavioral studies of the extrastriate visual cortex: In Tupaia bilateral removal of the striate cortex leaves form vision preserved to a remarkable extent, but a removal of striate and extrastriate visual cortex combined greatly prolongs learning of simple visual tasks, and lesions of the extrastriate alone produce deficits in visual learning. In Galago there is evidence that the temporal cortex also has a role in visual learning, but the exact area has never been defined in either species. The significance of these results lies in the discovery in the cat that the ablation of the middle suprasylvian area has a profound effect on transfer of training from one to the opposite hemisphere as well as on visual learning. Just the same combination of deficits--retarded visual learning and deficits in hemispheric transfer--are found in the monkey by lesion of the inferotemporal cortex. What is the significance of this correlation between hemispheric transfer and visual learning? That is the question posed in this application. The method is first to identify precisely an extrastriate visual learning area in Tupaia and Galago, and second to study this area with behavioral tests of hemispheric transfer. Physiological and anatomical studies of the role of the commissures in the function of the extrastriate cortex are also proposed. We already know that the function of the extrastriate visual area in the cat does not depend on striate cortex, while the opposite is true of the monkey. This species difference suggests the possibility of convergent evolution and our studies of two carefully chosen species, Tupaia and Galago, are designed to explain the puzzling similarities and differences between the cat and monkey.

该提案的起点是许多行为研究 外部视觉皮层：在Tupaia双边去除条纹 皮质留下的视力在一定程度上保存，但要删除 分层和腹部视觉皮层的结合大大延长 学习简单的视觉任务和单独的外室病变 在视觉学习中产生缺陷。 在加拉戈，有证据表明 颞皮质在视觉学习中也起作用，但确切的领域具有 从来没有在任何一种物种中定义。 这些结果的意义 在猫中发现中间的消融 Suprasylvian地区对训练从一个转移到 相反的半球以及视觉学习。 同样 缺陷的结合 - 延迟的视觉学习和缺陷 半球转移 - 通过病变在猴子中发现 上颞皮层。 这种相关的意义是什么 在半球传递和视觉学习之间？ 这就是问题 在此应用程序中摆姿势。 该方法首先确定 Tupaia和Galago的视觉学习区域外，其次是学习 该区域具有半球传递的行为测试。 生理和 关于委员在功能中的作用的解剖学研究 还提出了外层皮层。 我们已经知道该功能 猫中的腹腔外视区域不取决于条纹 皮质，而猴子的恰恰相反。 这个物种差异 提出了收敛进化的可能性以及我们对两个的研究 精心选择的物种Tupaia和Galago旨在解释 令人困惑的是猫和猴子之间的相似性和差异。