The natural function and evolution of an essential parasite transporter

重要寄生虫转运蛋白的自然功能和进化

• 批准号: FT160100226
• 负责人: Dr Rowena Martin
• 金额: $ 56.37万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT160100226
• 关键词: natural; function; evolution; essential; parasite

This project aims to resolve the natural function and evolution of a transporter essential to the survival of malaria and other parasites. Malaria and its sibling Apicomplexan parasites cause devastating diseases in humans and livestock across the world. Much remains to be understood about these parasites, and options for controlling them are diminishing. The project will interrogate the functions of the transporter proteins. The knowledge gained might help to combat Apicomplexan parasites by targeting these transporters’ native functions.

该项目旨在解决疟疾和其他寄生虫生存所必需的转运蛋白的自然功能和进化。疟疾及其兄弟姐妹顶复门寄生虫在世界各地的人类和牲畜中造成毁灭性的疾病。关于这些寄生虫还有很多东西需要了解，控制它们的选择也越来越少。该项目将询问转运蛋白的功能。所获得的知识可能有助于通过靶向这些转运蛋白的天然功能来对抗顶复门寄生虫。