HORMONAL INFLUENCES ON THE NEUROBIOL OF EXCITABLE CELLS
HORMONAL INFLUENCES ON THE NEUROBIOL OF EXCITABLE CELLS
批准号:
3400067
负责人:
ANDREW H BASS
金额:
$7.25万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1984
资助国家:
美国
项目状态:
已结题
起止时间:
1984-04-01 至 1987-03-31
关键词:
autoradiography central nervous system dihydrotestosterone electrolytes electron microscopy electrophysiology estradiol gender difference hormone regulation /control mechanism membrane structure molecular site neural information processing neuroanatomy neurochemistry neuroendocrine system saltwater environment steroid hormone testosterone
中文摘要
我们正在研究性腺激素对解剖学的影响,
电器官,电感受器,
和弱电鱼类的中枢神经通路,
象鼻虫科
电器官产生一种物种特有的电信号,
器官放电(E O D),这是重要的机制,
物种和性别识别。 爆炸物处理装置的特性
波形取决于电细胞的解剖和生理,
电器官的易兴奋细胞。 我们发现性腺
类固醇激素可在青少年中诱导雄性型爆炸物OD波形,
在EOD波形中具有自然性别差异的物种的雌性。 一
一组特殊的电感受器,产生刺突样感受器
电位,显示自然女性之间的频率调谐差异
以及具有经尿道诱导的雄性EOD波形的自然雄性或雌性。
我们将研究潜在的机制,在爆炸物处理引起的变化,
波形和电感受器调谐与电生理,解剖,
和生化技术。
我们还通过类固醇放射自显影术,
在中枢神经系统通路中的神经细胞聚集。 这些
研究结果将通过额外的放射自显影研究来扩展。 以来
中枢通路控制电器官兴奋的速率,即,
爆炸物处理节奏,我们将研究爆炸物处理节奏的可能差异
自然的雄性和雌性之间的差异,以及处理过的标本。
英文摘要
We are studying the influences of gonadal hormones on the anatomy and
physiology of the excitable cells of the electric organ, electroreceptors,
and the central electromotor pathway of the weakly electric fishes,
Mormyridae.
The electric organ produces a species-typical electrical signal, the
Electric Organ Discharge (E O D), which is important for mechanisms of
species and sex recognition. The characteristic properties of the EOD
waveform depend upon the anatomy and physiology of the electrocytes, the
excitable cells of the electric organ. We have discovered that gonadal
steroid hormones can induce a male-type EOD waveform among juveniles and
females of species with a natural sex difference in their EOD waveform. A
special set of electroreceptors, that produce spike-like receptor
potentials, show a difference in frequency tuning between natural females
and, natural males or females with a hormonally-induced male EOD waveform.
We will study the mechanisms underlying hormone-induced changes in EOD
waveforms and electroreceptor tuning with electrophysiological, anatomical,
and biochemical techniques.
We have also identified, using steroid autoradiography,
hormone-concentrating cells in the central electromotor pathway. These
findings will be extended with additional autoradiographic studies. Since
the central pathway controls the rate of electric organ excitation, i.e.
the EOD rhythm, we will examine possible differences in the EOD rhythm
between natural males and females, and hormone-treated specimens.
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会议论文
Acoustic modulation of forebrain aggression network in miniature, transparent vocal fish
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批准号:10524567
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项目类别:
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资助金额:$73.8万
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财政年份:2022
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负责人:ANDREW H BASS
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依托单位:
Encoding of Vocal Signals in the Auditory System
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批准号:7850248
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资助金额:$16.58万
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财政年份:2009
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负责人:ANDREW H BASS
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HORMONAL INFLUENCES ON THE NEUROBIOL OF EXCITABLE CELLS
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批准号:3400069
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项目类别:
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资助金额:$10.24万
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财政年份:1984
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负责人:ANDREW H BASS
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依托单位:
HORMONAL INFLUENCES ON THE NEUROBIOL OF EXCITABLE CELLS
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批准号:3400063
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项目类别:
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资助金额:$12.42万
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财政年份:1984
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负责人:ANDREW H BASS
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依托单位:
HORMONAL INFLUENCES ON THE NEUROBIOL OF EXCITABLE CELLS
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批准号:3400070
-
项目类别:
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资助金额:$8.9万
-
财政年份:1984
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负责人:ANDREW H BASS
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依托单位:
HORMONAL INFLUENCES ON THE NEUROBIOL OF EXCITABLE CELLS
-
批准号:3400068
-
项目类别:
-
资助金额:$6.75万
-
财政年份:1984
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负责人:ANDREW H BASS
-
依托单位:
ENCODING OF VOCAL SIGNALS IN THE AUDITORY SYSTEM
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批准号:2608231
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项目类别:
-
资助金额:$23.53万
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财政年份:1974
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负责人:ANDREW H BASS
-
依托单位:
Encoding of Vocal Signals in the Auditory System
-
批准号:7324086
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项目类别:
-
资助金额:$32.24万
-
财政年份:1974
-
负责人:ANDREW H BASS
-
依托单位:
ENCODING OF VOCAL SIGNALS IN THE AUDITORY SYSTEM
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批准号:6329185
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项目类别:
-
资助金额:$24.31万
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财政年份:1974
-
负责人:ANDREW H BASS
-
依托单位:
Encoding of vocal Signals in the Auditory System
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批准号:6792625
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项目类别:
-
资助金额:$35.72万
-
财政年份:1974
-
负责人:ANDREW H BASS
-
依托单位:
Encoding of Vocal Signals in the Auditory System
-
批准号:7534027
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项目类别:
-
资助金额:$32.2万
-
财政年份:1974
-
负责人:ANDREW H BASS
-
依托单位:
Encoding of Vocal Signals in the Auditory System
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批准号:7701457
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项目类别:
-
资助金额:$31.83万
-
财政年份:1974
-
负责人:ANDREW H BASS
-
依托单位:
ENCODING OF VOCAL SIGNALS IN THE AUDITORY SYSTEM
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批准号:2014203
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项目类别:
-
资助金额:$22.64万
-
财政年份:1974
-
负责人:ANDREW H BASS
-
依托单位:
Encoding of Vocal Signals in the Auditory System
-
批准号:7986349
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项目类别:
-
资助金额:$30.77万
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财政年份:1974
-
负责人:ANDREW H BASS
-
依托单位:
ENCODING OF VOCAL SIGNALS IN THE AUDITORY SYSTEM
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批准号:2124524
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项目类别:
-
资助金额:$27.39万
-
财政年份:1974
-
负责人:ANDREW H BASS
-
依托单位:
Encoding of vocal Signals in the Auditory System
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批准号:6547628
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项目类别:
-
资助金额:$35.72万
-
财政年份:1974
-
负责人:ANDREW H BASS
-
依托单位:
ENCODING OF VOCAL SIGNALS IN THE AUDITORY SYSTEM
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批准号:6124940
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项目类别:
-
资助金额:$23.72万
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财政年份:1974
-
负责人:ANDREW H BASS
-
依托单位:
ENCODING OF VOCAL SIGNALS IN THE AUDITORY SYSTEM
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批准号:2837920
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项目类别:
-
资助金额:$23.14万
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财政年份:1974
-
负责人:ANDREW H BASS
-
依托单位:
Encoding of Vocal Signals in the Auditory System
-
批准号:7213567
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项目类别:
-
资助金额:$27.82万
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财政年份:1974
-
负责人:ANDREW H BASS
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依托单位:
Encoding of vocal Signals in the Auditory System
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批准号:6649251
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项目类别:
-
资助金额:$35.72万
-
财政年份:1974
-
负责人:ANDREW H BASS
-
依托单位:
海外基金