2023 Central Nervous System Injury and Repair Gordon Research Conference and Seminar

2023中枢神经系统损伤与修复戈登研究会议暨研讨会

• 批准号: 10753737
• 负责人: Yishi Jin
• 金额: $ 2.15万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-05 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10753737
• 关键词: Acceleration; Achievement; Advocate; Age; Age Distribution; Animal Model; Applications Grants; Area; Atmosphere; Basic Science; Biological Models; Bladder Dysfunction; COVID-19 pandemic; Cells; Cellular biology; Central Nervous System; Charities; Clinical Research; Communication; Consensus; Data; Development; Disadvantaged; Disease; Education; Ensure; Environment; Ethnic Origin; Face; Faculty; Fostering; Friends; Future; Gender; Geographic Distribution; Geographic Locations; Goals; Hour; Immune; Industrialization; Industry; Injury; International; Interruption; Interview; Italy; Life; Mediation; Medical; Mentors; Molecular; Molecular Biology; Natural regeneration; Neuroglia; Neurons; Numbness; Occupations; Oral; Pain; Paralysed; Participant; Patient Care; Patients; Persons; Physicians; Positioning Attribute; Postdoctoral Fellow; Publishing; Recovery of Function; Renaissance; Reporting; Research; Research Institute; Research Personnel; Science; Scientist; Series; Sexual Dysfunction; Social Interaction; Spinal cord injury; Time; Translations; Underrepresented Minority; Universities; Woman; Work; age group; axon injury; career; career development; cell type; central nervous system injury; clinical application; clinical practice; combinatorial; disability; effective therapy; experience; graduate student; injury and repair; innovation; interest; meetings; nerve injury; nerve repair; neural circuit; neuronal circuitry; novel; peer networks; posters; programs; repaired; response to injury; restoration; social; stem cells; symposium

Project Summary: The 2023 Gordon Research Conference (GRC) series, entitled “Central Nervous System Injury and Repair”, together with its accompanying Gordon Research Seminar (GRS), will bring together interactional researchers at all levels to discuss progress and challenges for CNS injury, regeneration, and repair, with particular emphasis on spinal cord injury. Spinal cord injury is a major medical challenge since it leaves millions of people worldwide paralyzed and with loss of sensation, cardiorespiratory, bladder, and sexual dysfunction as well as pain for their lifetime. Despite many years of efforts, effective treatment remains lacking. This is in part due to the complexity of this disease where in addition to the damage of axons, spinal cord injury leads to profound changes in the cellular and molecular environment, involving neurons, glia, immune cells, and other cell types. An emerging consensus is that combinatorial approaches targeting multiple cellular and molecular aspects of the injury response will be necessary to treat spinal cord injury and induce functional recovery. At this conference, we will showcase the most exciting and cutting-edge scientific progress in this field, with the goal of collectively accelerating the discovery and translation of treatments that will lead to functional recovery. The conference speakers cover broad topics from basic mechanisms in neuronal circuitry and axonal injury in animal models, clinical application, and progress in stem cell programming, through to clinical practice and patient care. The discussion will be encouraged both formally in the scientific sessions and informally during poster sessions and time set aside for social interactions. The accompanying GRS will serve as an interactive forum for trainees to communicate their research and broaden their peer network. The GRC will also feature a Power Hour, open to all attendees, to discuss challenges we face, particularly women, underrepresented minorities, disadvantaged researchers, and trainees. We expect a large attendance from basic and physician-scientists, as well as representation from industry. We also anticipate a breadth of diversity across gender, ethnicity, disability, age, and geographical location that will ensure a broad and inclusive communication of the scientific content.

项目概要： 2023年戈登研究会议（GRC）系列，题为“中枢神经系统损伤和修复”，连同其伴随的戈登研究研讨会（GRS），将汇集各级研究人员，讨论中枢神经系统损伤，再生和修复的进展和挑战，特别强调脊髓损伤。脊髓损伤是一个重大的医学挑战，因为它使全世界数百万人瘫痪，失去感觉，心肺功能，膀胱功能和性功能障碍以及终身疼痛。尽管多年努力，仍然缺乏有效的治疗。这部分是由于这种疾病的复杂性，其中除了轴突的损伤之外，脊髓损伤还导致细胞和分子环境的深刻变化，涉及神经元，神经胶质细胞，免疫细胞和其他细胞类型。一个正在形成的共识是，针对损伤反应的多个细胞和分子方面的组合方法将是治疗脊髓损伤和诱导功能恢复所必需的。在这次会议上，我们将展示该领域最令人兴奋和最前沿的科学进展，目标是共同加速发现和翻译将导致功能恢复的治疗方法。会议发言人涵盖了广泛的主题，从动物模型中神经元电路和轴突损伤的基本机制，临床应用，干细胞编程的进展，到临床实践和患者护理。将鼓励在科学会议上正式讨论，在海报会议上非正式讨论，并留出时间进行社会互动。随附的GRS将作为一个互动论坛，供学员交流他们的研究和扩大他们的同行网络。GRC还将举办Power Hour，向所有与会者开放，讨论我们面临的挑战，特别是女性，代表性不足的少数民族，弱势研究人员和学员。我们期待着大量的基础和物理科学家的出席，以及来自行业的代表。我们还预计性别，种族，残疾，年龄和地理位置的多样性将确保科学内容的广泛和包容性传播。