Nano-agents for read / write microscopy and nano-macro bridging

用于读/写显微镜和纳米宏观桥接的纳米试剂

• 批准号: EP/K021877/1
• 负责人: Matthew Clark
• 金额: $ 188.52万
• 依托单位: University of Nottingham
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2013
• 资助国家: 英国
• 起止时间: 2013 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FK021877%2F1
• 关键词: Nano; agents; read; write; microscopy

The nanoscale is extremely important to our world, for instance:- At this scale many of properties of materials we use at the macroscale are determined- Many biological systems have structure at the nanoscale and operate through series of reactions that take place on the nanoscaleCommunicating with the nanoscale is increasingly important for our understanding of our wider world, however, it is much more difficult to do this than at larger scales. There are lots of tools for probing things at the small scale but these have many drawbacks, for instance, optical microscopy does not have sufficient resolution to see things at the nanoscale; atomic force microscopy, which is often used to image object at the nanoscale, can't see inside things like cells; and electron microscopy which is widely used to image and write objects at the nanoscale can't be used on large or living objects.This proposal aims to develop a new method of communicating with the nanoscale by using small devices, "nano-agents", which can get information in and out of the nanoscale environment. These will operate remotely and without contact with the instrument so they can be placed inside objects, even large and living ones. They will enable the nanoscale environment to be sensed and provide a way to change the nanoscale environment. This will open up new ways to explore and interact with the nanoscale.

纳米尺度对我们的世界非常重要，例如：-在这个尺度上，我们在宏观尺度上使用的材料的许多属性都是确定的-许多生物系统具有纳米尺度的结构，并通过在纳米尺度上发生的一系列反应进行操作与纳米尺度的交流对于我们理解更广阔的世界越来越重要，然而，这比在更大的尺度上更难做到这一点。有很多工具可以在小尺度上探测事物，但这些工具有很多缺点，例如，光学显微镜没有足够的分辨率来观察纳米尺度的事物;原子力显微镜通常用于在纳米尺度上对物体进行成像，无法看到细胞等内部事物;电子显微镜被广泛用于纳米级物体的成像和书写，但不能用于大型或活体物体。这项提议旨在开发一种新的与纳米级物体通信的方法。通过使用小型设备，“纳米代理”，它可以在纳米级环境中获取信息。这些将远程操作，无需与仪器接触，因此它们可以放置在物体内部，甚至是大型和活体物体。它们将使纳米级环境能够被感知，并提供一种改变纳米级环境的方法。这将为探索和与纳米级互动开辟新的途径。

项目成果

Cell imaging using sub-optical wavelength ultrasonics

使用亚光波长超声波进行细胞成像

• DOI: 10.1364/acpc.2015.asu5h.1
• 发表时间: 2015
• 作者: Clark M

Polarization-Sensitive Super-Resolution Phononic Reconstruction of Nanostructures.

• DOI: 10.1021/acsphotonics.1c01607
• 发表时间: 2022-06-15
• 期刊: ACS PHOTONICS
• 影响因子: 7
• 作者: Fuentes-Dominguez, Rafael;Naznin, Shakila;La Cavera, Salvatore, III;Cousins, Richard;Perez-Cota, Fernando;Smith, Richard J.;Clark, Matt
• 通讯作者: Clark, Matt

Enhanced sensing and conversion of ultrasonic Rayleigh waves by elastic metasurfaces.

• DOI: 10.1038/s41598-017-07151-6
• 发表时间: 2017-07-28
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Colombi A;Ageeva V;Smith RJ;Clare A;Patel R;Clark M;Colquitt D;Roux P;Guenneau S;Craster RV
• 通讯作者: Craster RV

Super-resolution imaging using nano-bells.

• DOI: 10.1038/s41598-018-34744-6
• 发表时间: 2018-11-06
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Fuentes-Domínguez R;Pérez-Cota F;Naznin S;Smith RJ;Clark M
• 通讯作者: Clark M

Characterising the size and shape of metallic nano-structures by their acoustic vibrations

• DOI: 10.1039/d0nr03410j
• 发表时间: 2020-07-14
• 期刊: NANOSCALE
• 影响因子: 6.7
• 作者: Fuentes-Dominguez, Rafael;Naznin, Shakila;Clark, Matt
• 通讯作者: Clark, Matt