SYMPOSIUM ON CEREBRAL HYPOXIA AND STROKE

脑缺氧与中风研讨会

• 批准号: 3436084
• 负责人: GEORGE G SOMJEN
• 金额: $ 1.24万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-07-01 至 1987-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3436084
• 关键词: cerebral ischemia /hypoxia; stroke; travel

The symposium CEREBRAL HYPOXIA AND STROKE: reversible and irreversible effects and their prevention will be an independent satellite meeting of the Second World Congress of Neuroscience. It will be held after the main Congress at the Institute of Pathophysiology of Semmelweis Medical University in Budapest. This application requests support for the preparation of the scientific program and partial funding of travel by invited speakers. The purpose of the symposium is to review basic research of the morphology, biochemistry and physiology of cerebral hypoxia and ischemia. The three-day program will consist of invited communications (lecture format), volunteer poster communications and a targeted general discussion. Topics to be covered include: (1) The mechanism of reversible synaptic blockade caused by hypoxia. (2) Paroxysmal firing and hyperexcitability during and after hypoxia. (3) The apreading depression-like depolarization caused by hypoxia. (4) Redistribution of ions in neurons and glial cells during and after hypoxia. (5) Biochemical changes in hypoxic brain tissue. (6) Immediate and delayed cell death in hypoxia and ischemia: the noxae that damage neurons. (7) Morphological, biochemical and physiological aspects of irreversible damage to neurons. (8) Prophylaxis and therapy of hypoxic and ischemic brain damage. (9) Brain protection in diving mammals. All invited papers and selected volunteer abstracts will be published in a monograph. This volume will also contain a synopsis of the general discussion and a concluding summary chapter that will serve as a review of the current state of research as well as prospects for prophylaxis and therapy.

脑缺氧和中风：可逆性 和不可逆转的影响和预防将是一个 第二届世界反腐败大会独立附属会议 神经科学 会议将在主要代表大会结束后在 塞麦尔维斯医科大学病理生理学研究所 布达佩斯。 此应用程序请求支持编写 科学计划和部分资金的旅行邀请 扬声器. 研讨会的目的是审查基础研究的 脑缺氧的形态学、生物化学和生理学， 缺血 为期三天的节目将包括邀请 交流（讲座形式），志愿者海报 沟通和有针对性的一般性讨论。 议题 涵盖的项目包括： (1)引起可逆性突触阻滞的机制 缺氧 (2)术中和术后阵发性放电和过度兴奋 缺氧 (3)由磁共振成像引起的近似凹陷状去极化 缺氧 (4)期间和期间神经元和神经胶质细胞中离子的重新分布 缺氧后。 (5)缺氧脑组织的生化变化。 (6)缺氧和缺血中的即时和延迟细胞死亡： 伤害神经元的毒素 (7)形态学、生物化学和生理学方面 对神经元造成不可逆的损伤 (8)缺氧缺血性脑损伤的防治 损害 (9)潜水哺乳动物的脑保护。 所有邀请的论文和选定的志愿者摘要将 发表在一本专著中。 该卷还将包含一个 一般性讨论概要和结论性摘要 这一章将作为对目前状况的审查， 研究以及预防和治疗的前景。