CENTRAL NERVOUS SYSTEM TRANSPLANTATION

中枢神经系统移植

• 批准号: 3436078
• 负责人: JOHN RICHARD SLADEK
• 金额: $ 2.53万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-04-01 至 1988-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3436078
• 关键词: Parkinson's disease; axon; disease /disorder model; graft versus host disease; meeting /conference /symposium; nervous system transplantation; neurochemistry

The First International Symposium of Transplantation into the mammalian CNS was held at Orenas Castle near Lund, Sweden, on June 18-22, 1984. Scientists throughout the world gathered to review the experimental basis for neural tansplantation and to discuss future directions of what has become a rapidly developing subdiscipline in neurobiology. The Conference provided numerous insights, both retrospective and prospective on the feasibility to nerve cell grafting to reverse neurological deficits in numerous model systems. It also raised provocative questions about the future. We will review new information dealing with transplantation into the primate central nervous system in animal models of Parkinson's disease, for example, and will explore the use of tissue donors alternate to fetuses as a practical approach to therapeutic grafting. New vistas in our understanding of trophic substances and exciting parameters on mechanical and neurochemical guidance of growing axons following transplantation will be explored. Numerous other topics as detailed in the application will serve to balance the meeting with respect to basic understanding of graft host interactions. The Second International Symposium maintains the organizational structure of the first meeting as well as the guiding principles of program selection. It is in part supported by philantropic efforts and a host university, but due to the expansion of the size of the meeting to meet the growth of the discipline, it will be necessary to generate financial assistance beyond that already dedicated to the Conference.

首届心脏移植国际学术研讨会 哺乳动物CNS被关押在瑞典隆德附近的奥雷纳斯城堡 1984年6月18日至22日。世界各地的科学家齐聚一堂 综述神经移植的实验基础及研究进展 讨论已经迅速发展的未来方向 神经生物学的分支学科。会议提供了许多 对以下项目的可行性的回顾和前瞻性见解 神经细胞移植逆转众多患者的神经功能缺陷 模型系统。它还提出了一些挑衅性的问题 未来。我们将回顾处理以下问题的新信息 动物中枢神经系统移植的实验研究 例如，帕金森氏病模型，并将探索 使用替代胎儿的组织供体是一种实用的方法 到治疗性嫁接。在我们的理解中展现新的前景 机械和机械的营养物质和激发参数 生长轴突的神经化学指导 将对移植进行探索。许多其他主题，如 申请表中的详细信息将有助于平衡会议与 尊重对移植物宿主相互作用的基本理解。 第二届国际研讨会维护组织 第一次会议的结构以及#年的指导原则 节目选择。这在一定程度上是由亲女性的努力支持的。 和一所主办大学，但由于规模的扩大 满足学科发展需要的会议，将是必要的 在已经专门用于的财政援助之外创造财政援助 会议。