1986 GORDON RESEARCH CONFERENCE--ENZYMES & COENZYMES

1986年戈登研究会议--酶

• 批准号: 3434956
• 负责人: NORMAN J OPPENHEIMER
• 金额: $ 0.2万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 1986
• 资助国家: 美国
• 起止时间: 1986-06-29 至 1986-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3434956
• 关键词: chemical structure function; cofactor; enzymes; genetic manipulation; meeting /conference /symposium; point mutation

Support is requested for the Gordon Research Conference on Enzymes, Coenzymes and Metabolic Pathways which will be held at Kimball Union Academy, Meriden, New Hampshire from June 29 through July 4, 1986. This conference is intended to extend the frontiers of science by fostering free and informal exchange of information among scientists who function at the interface between chemistry and biology. The underlying themes of this conference involve detailed studies of enzymatic reactions and the cofactors involved in these reactions and how the activity of these enzymes and whole metabolic pathways are controlled. This year the conference will have a special emphasis on applications of site-directed mutagenesis for the study of enzyme mechanisms. Included will be analysis of the consequences of amino acid replacements in order to predict the properties of the modified proteins and to evaluate the implications of structural changes for understanding the origins of enzyme catalysis. A balance will be maintained between talks concerned with presentation of detailed experimental results with those dealing with the development of new techniques. In all cases, scheduled speakers have been selected on the basis of their excellence in research and the presentation of significant new advances. The participation in this conference of experts in recombinant DNA techniques, x-ray crystallography, physical organic chemistry, bio-organic chemistry and enzyme mechanisms should result in new and exciting collaborations.

请求支持戈登酶研究会议， 辅酶和代谢途径将在 Kimball Union 举行 1986 年 6 月 29 日至 7 月 4 日，新罕布什尔州梅里登学院。 会议旨在通过促进自由发展来扩展科学前沿 以及在该机构工作的科学家之间非正式的信息交流 化学和生物学之间的界面。 本次会议的基本主题涉及以下方面的详细研究 酶促反应和参与这些反应的辅因子以及如何 这些酶的活性和整个代谢途径受到控制。 今年的会议将特别强调应用 用于研究酶机制的定点诱变。 包括 将分析氨基酸替代的后果，以便 预测修饰蛋白质的特性并评估 结构变化对理解酶起源的影响 催化。 相关谈判之间将保持平衡 向那些处理该问题的人介绍详细的实验结果 新技术的开发。 在所有情况下，预定的发言人均已 根据他们在研究和演讲方面的卓越表现而选择 的重大新进展。 参加本次会议的有 重组 DNA 技术、X 射线晶体学、物理 有机化学、生物有机化学和酶机制应该 带来新的、令人兴奋的合作。