PROTEIN FOLDING AND ASSEMBLY IN THE CELL

这是一份申请“蛋白质”会议部分资金的申请书。 “在细胞中折叠和组装”将由 美国实验生物学学会联合会(FASEB)，来自 1990年6月24日至29日，科罗拉多州铜山。这次会议是 意在首次将多组学术科学家聚集在一起 以及生物技术专家，他们一直在非常不同的领域工作，但 现在对蛋白质折叠的兴趣迅速汇聚。扬声器和 会议的参与者将包括参与一项 蛋白质折叠、蛋白质转运、蛋白质研究的多样性 降解和应激蛋白家族。这些研究人员中将包括 那些在理论方面和体外系统工作的人，以及那些 在体内研究各种系统，如原核生物、酵母、植物和 哺乳动物细胞。中心主题将是蛋白质折叠是如何实现的 并在细胞内受到调节。 会议将由九个科学会议组成，每个会议有四到 六位演讲者和一位讨论负责人。将涵盖的主题包括：结构 蛋白质折叠的决定因素--理论和体外研究“， 《蛋白质折叠的遗传学研究》、《细胞蛋白质参与 蛋白质折叠(I和II)，折叠在蛋白质易位中的作用 跨膜“，”蛋白质折叠和细胞内运输“，”折叠“ 和异构体多亚单位蛋白的组装杂交种的性质 蛋白质“和”蛋白质的错误折叠、聚集和胞内 此外，每天还将举行一次海报会议，以允许更多 初级参与者介绍他们的工作。参与的人数将仅限于 150名科学家(包括演讲者和讨论负责人)，他们将是 根据他们的专业知识和兴趣选择，最有可能 为创造一个激励和富有成效的环境作出贡献。

This is an application for partial funding of a conference on "Protein Folding and Assembly in the Cell" to be held under the auspices of the Federation of American Societies for Experimental Biology (FASEB), from June 24 to 29, 1990 in Copper Mountain, Colorado. The conference is intended to bring together for the first time groups of academic scientists and biotechnologists who have been working in very diverse areas but have now have a rapidly converging interest in protein folding. Speakers and participants at the conference will include researchers involved in a variety of studies on protein folding, protein transport, protein degradation and the stress protein family. Among these researchers will be those working on theoretical aspects and in vitro systems, as well as those working in vivo on systems as diverse as prokaryotes, yeasts, plants and mammalian cells. The central theme will be how protein folding is achieved and regulated within the cell. The conference will consist of nine scientific sessions, each with four to six speakers and a discussion leader. Topics to be covered are: "Structural Determinants of Protein Folding - Theoretical and In Vitro Studies", "Genetic Studies of Protein Folding", "Cellular Proteins Involved in Protein Folding (I and II)", "Role of Folding in Protein Translocation Across Membranes", "Protein Folding and Intracellular Transport", "Folding and Assembly of Heteromeric Multisubunit Proteins", "Properties of Hybrid Proteins" and "Protein Misfolding, Aggregation and Intracellular Degradation". In addition a poster session will be held daily to allow more junior participants to present their work. Participation will be limited to 150 scientists (including the speakers and discussion leaders), who will be selected on the basis of their expertise and interests as most likely to contribute to a stimulating and productive environment.