ECOLOGY AND CONTROL OF ARBOVIRUSES

虫媒病毒的生态学和控制

• 批准号: 3444413
• 负责人: JAMES L HARDY
• 金额: $ 49.73万
• 依托单位: UNIVERSITY OF CALIFORNIA BERKELEY
• 依托单位国家: 美国
• 财政年份: 1974
• 资助国家: 美国
• 起止时间: 1974-09-01 至 1990-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3444413
• 关键词: Togaviridae; communicable disease control; communicable disease transmission; ecology; environmental health; epidemiology; temperature; virus genetics

The long-term objective of this project is to gain a sufficient knowledge of the ecology of arboviruses for development of effective strategies to control those arboviral diseases that are of public health and veterinary importance in North America. Six areas of research are proposed currently to attain this objective: laboratory studies to elucidate instrinsic factors and mechanisms that control the competence of selected mosquito species to vector arboviruses that cause epidemics; controlled laboratory studies to determine the effect of temperature on the extrinsic incubation of arboviruses in their mosquito vectors and parallel field studies to evaluate the role of temperature as an environmental factor that influences the seasonal and yearly patterns of western equine encephalomyelitis and St. Louis encephalitis viruses; in-depth field studies on the ecology of WEE virus and its vectors in rural agricultural and riparian/marshland habitats in Kern County, California to identify basic foci of viral transmission and patterns of dissemination from such foci; study of alternative hypotheses to explain the overwintering of 6 enzootic arboviruses in their arthropod vectors and vertebrate hosts in Kern County, California; to develop statistical-epidemiological models that will integrate the variables that control mosquito population growth and associated arboviral transmission cycles including the impact of alternative strategies for control of vector populations; and to summarize research accomplishments during the past 40 years in the form of a monograph on "The Epidemiology of the Arthropod-borne Viruses in California, 1943-1984."

这个项目的长期目标是获得足够的知识