PLASMA SKIMMING OF BLOOD IN BIFURCATIONS IN SERIES

这项拟议的研究解决了血管内血浆撇除的问题。 使用两个分叉的体外复制进行实验的网络 充满红细胞的网络(分支直径10到50 Mum) 停职。测量红血球速度和红细胞流可以 由Sorelius和Duling的荧光标记技术实现 (1982)。容量氟化物和红细胞流量的测量将会到来 来自网络副本的每个分支的流出水的收集。 来自这项工作的数据和分析将有助于体内微循环学者 解读他们对网络血流的研究结果。所获得的数据为 适用于生理问题的血流调节和02 送货。 更真实的计算机网络模型可以从 预期数据。计算机模型的价值在于模拟 他们可以进行的实验，不能在体内进行，在血管中进行 疾病研究。这些类型的仿真实验具有一定的应用价值 高血压和糖尿病。

The proposed research attacks the problem of plasma skimming in vascular networks with experiments using in vitro replicas of two bifurcation networks (branch diameter 10 to 50 Mum) perfused with red cell suspensions. Measurements of red cell velocity and red cell flux can be accomplished by the fluorescent labelling technique of Sorelius and Duling (1982). Measurements of volumetric fluorates and red cell flux will come from collection of effuent from each branch of the network replica. The data and analysis from this work will help in vivo microcirulationists interpret their results on network blood flow. The data obtained is applicable to the physiological problems of blood flow regulation and 02 delivery. More realistic computer network models can be developed from the anticipated data. The value of computer models is the simulation experiments they can perform, which cannot be done in vivo, in vascular disease research. These types of simulation experiments have application in hypertension and diabetes.