Clinical implications of trans-kingdom microbial interactions in the transplanted lung

移植肺中跨界微生物相互作用的临床意义

• 批准号: nhmrc : 1146982
• 负责人: A/Pr Glen Westall
• 金额: $ 42.14万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/clinical-implications-trans-transplanted-lung/1320772
• 关键词: Clinical; implications; trans; kingdom; microbial

Lung transplantation is a critical requirement for people with severe lung diseases. The lung is constantly exposed to bugs and viruses, which reside in the airways, and can be both beneficial or detrimental for lung health. This interaction between the immune system and these bugs can influence the health and longevity of the lung transplant. We aim to discover how we could target these interactions to improve the long-term success of lung transplantation.

肺移植是严重肺部疾病患者的关键要求。肺部不断暴露于存在于气道中的细菌和病毒，对肺部健康既有利又有害。免疫系统和这些细菌之间的相互作用会影响肺移植的健康和寿命。我们的目标是发现如何针对这些相互作用来提高肺移植的长期成功率。