Clinical and neurobiological predictors of onset of major mental disorders (mania, psychosis, severe depression), and associated functional impairment, in adolescent and young adult twins: A prospective longitudinal study

青少年和年轻成人双胞胎中主要精神障碍（躁狂、精神病、严重抑郁）以及相关功能障碍发作的临床和神经生物学预测因素：一项前瞻性纵向研究

• 批准号: nhmrc : 1069141
• 负责人: A/Pr James Scott
• 金额: $ 90.42万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/clinical-neurobiological-predictors-longitudinal-study/455372
• 关键词: Clinical; neurobiological; predictors; onset; major

The Brisbane Twin Study is a prospective twin study tracking the real-time developmental trajectories of the onset of anxiety, mood, psychotic or substance misuse disorders through adolescence and young adulthood. This unique study has now reached the point where reassessment (after 20 years) can be performed. We will now determine the extent to which outcomes are predicted by neurobiological and genetic markers. This information is critical to prevention or early intervention strategies.

布里斯班双胞胎研究是一项前瞻性双胞胎研究，跟踪青少年和青年期焦虑、情绪、精神病或物质滥用障碍发作的实时发展轨迹。这项独特的研究现在已经到了可以进行重新评估（20年后）的地步。我们现在将确定神经生物学和遗传标记预测结果的程度。这些信息对于预防或早期干预战略至关重要。