IDENTIFICATION AND QUANTITATION OF DRUGS IN BODY FLUIDS

体液中药物的鉴定和定量

• 批准号: 3494190
• 负责人: JOSEPH R STETTER
• 金额: $ 4.22万
• 依托单位: TRANSDUCER RESEARCH, INC.
• 依托单位国家: 美国
• 财政年份: 1986
• 资助国家: 美国
• 起止时间: 1986-09-30 至 1987-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3494190
• 关键词: analytical chemistry; body fluids; clinical biomedical equipment; drug controls; electrochemistry; high performance liquid chromatography; online computer; pharmacokinetics

New techniques that improve the portability, selectivity, sensitivity, and economy of drug assays are important to the mission of the National Institute on Drug Abuse (NIDA). Recent advances in electrochemical detectors and dector arrays, portable instrument design, and applied artificial intelligence are combined in the proposed work. The result is a low-cost, portable, and highly selective liquid chromatograph for the qualitative and quantitative analysis of drugs in body fluids. In this Phase I SBIR research, an apparatus is assembled and tested in order to evaluate the feasibility of portable LCEC system that has exceptional analytical capabilities. The resultant device will have a microcomputer and software to allow automated analyses and make the equipment easy to use.

新技术提高了可移植性、选择性、灵敏度和