ULTRASONICALLY ACTIVATED SCALPEL FOR BLOODLESS SURGERY

用于无血手术的超声波激活手术刀

• 批准号: 3497917
• 负责人: ALAN E THOMAS
• 金额: $ 4.97万
• 依托单位: ENERGY AND MINERALS RESEARCH COMPANY
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-01-01 至 1987-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3497917
• 关键词: clinical biomedical equipment; hemostasis; plastic surgery; surgery; surgical wound; ultrasound; ultrasound biological effect; ultrasound therapy

There exists a demand on the part of dermatologists and plastic surgeons to produce well controlled, bloodless incisions. While the common, cold-steel scalpel provides surgeons with control over length and depth of cut (dependent on individual skills), the surgical field is not bloodless. For many applications, a self-cauterizing blade would be clearly advantageous. Surgical devices such as lasers, electrochemical cauteries, heated scalpels and ultrasonic probes are currently in use. Disadvantages associated with the use of these devices include tissue damage, scarring and increased risk of infection. Recently, an ultrasonic aspirator has been introduced. While this aspirator proved effective for certain liver resection procedures, it is not effective in cutting through pliable tissue such as stomach walls. Energy and Minerals Research Company has introduced an ultrasonically activated knife for industrial use called the ULTRAKNIFEtm. This tool cuts a wide variety of materials using markedly lower force. Other ultrasonically activated surgical devices induce mild hemostasis with little damage to surrounding tissues. We believe a modified version of our knife will be a superior scalpel that will also induce hemostasis during surgery. A research prototype ultrasonically activated scalpel will be assembled based on the findings of the research program and delivered to the Dermatology Group of the University of Pennsylvania Hospital for evaluation. Their evaluation will comprise part of the Final Report for Phase I. If the evaluation is positive, a Phase II program to develop a ultrasonic scalpel will be proposed. Though no market studies exist to determine the dollar value of a market for such a tool, we expect that demand will be widespread throughout the medical industry.

皮肤科医生和整形外科医生需要 制造出控制良好的、不流血的伤口。而普通的冷钢 手术刀使外科医生可以控制切割的长度和深度 (取决于个人技能)，外科手术领域并不是不流血的。为 在许多应用中，自烧蚀刀片显然是有利的。 外科设备，如激光、电化学烧灼器、加热手术刀 超声波探头目前正在使用中。与以下方面相关的劣势 这些设备的使用包括组织损伤、疤痕形成和增加风险。 感染的可能性。最近，一种超声波吸引器被推出。 虽然这种吸引器被证明对某些肝脏切除有效 手术，在切割柔韧组织时无效，如 胃壁。能源和矿产研究公司推出了一种 超声波激活的工业用刀称为ULTRAKNIFETM。 该工具使用明显较低的力切割各种材料。 其他超声激活的外科设备可以通过以下方式产生轻微止血 对周围组织的损伤很小。我们相信我们的修改版本 刀将是一把上等的手术刀，也将在 做手术。一种研究原型超声激活的手术刀将是 根据研究计划的结果进行组装，并交付给 宾夕法尼亚大学医院皮肤科小组 评估。他们的评价将构成#年最后报告的一部分。 阶段I如果评估是肯定的，则阶段II计划将制定 超声刀将被提出。尽管目前还没有市场研究来 确定这类工具的市场美元价值，我们预计 需求将在整个医疗行业广泛存在。