2022 Hemostasis Gordon Research Conference and Seminar

项目总结/文摘

Project Summary/Abstract We request partial support for the Hemostasis Gordon Research Seminar (GRS) and Gordon Research Conference (GRC), July 31-August 5, 2022, in Waterville Valley, NH. The 2022 Hemostasis GRC is the 35th meeting in this series which is widely considered as the premier scientific meeting for hemostasis and thrombosis research. This important topic closely aligns with NIH strategic goals in two critical areas: 1) to understand mechanisms and reduce morbidity and mortality from hemostatic and thrombotic diseases, including stroke, myocardial infarction, venous thromboembolism, and trauma-induced coagulopathy and 2) to increase the biomedical research workforce. Furthermore, recent research has shown that the traditionally considered hemostatic system has wider importance beyond clotting, playing roles in inflammation, innate immunity, obesity, diabetes, and cancer. The Hemostasis GRS/GRC brings together researchers interested in the biology, biochemistry, and genetics of blood clotting proteins and platelets; physicians treating bleeding and thrombotic diseases, scientists from pharmaceutical companies developing new therapies for hemostatic disorders, and trainees and junior faculty who are committed to research careers in hemostasis and thrombosis. Together, these investigators discuss state-of-the-art research and explore new research opportunities in hemostasis and thrombosis and their applications in medically related fields. Indeed, many key advances in this field have debuted at previous Hemostasis GRCs. Internationally renowned scientists engage and motivate trainees and junior investigators through close interactions and interactive exchanges. Free exchange of ideas and unpublished research, among all attendees, is a key to our GRS/GRC. Also, a priority is participation by women, underrepresented populations, individuals with physical disabilities, and young investigators, including graduate and postdoctoral trainees, and junior faculty. The 2022 Hemostasis GRS is specifically dedicated to the goal of enhancing the biomedical research workforce through trainee development activities and mentoring The GRS is organized and run by trainees. It is highly successful and enhances the profile of trainees at the GRC. The 2022 Hemostasis GRC program includes keynote addresses from two highly successful scientists, Drs. Robert Montgomery and Edward Plow, 39 talks, and posters. The 8 oral and 4 poster sessions focus on topics including Coagulation: Signaling and Structure; Coagulation and Platelets in Inflammation; Maintaining Hemostatic Balance; Clot and Deep Vein Thrombosis Structure; Lessons of Molecular Hemostasis from Organisms that Feed on Blood; Coagulation and Platelets in Chronic Diseases; and Bleeding and Clotting Control. Importantly, we will continue the practice of holding a “Hot Topics” session of abstract-derived talks during which 8 trainees present their work.