CATALYTIC ANTIBODIES FOR THERAPEUTIC APPLICATIONS

这项研究的长期目标是产生抗体 用于治疗应用的催化剂。具体地说，我们将准备 抗体催化剂可灭活艾滋病病毒并提供抗肿瘤 用于治疗癌症的药物转移到肿瘤部位。后续 商业化将包括开发治疗其他疾病的方法 病毒性疾病和解毒剂的制备。这个 针对来自这些半抗原的抗原的治疗性催化抗体。 设计这些半抗原的一种新方法包括使用 氨基膦酸类和基于酶机制的分析。

The long term objectives of this research are to generate antibody catalysts for therapeutic applications. Specifically, we will prepare antibody catalysts to inactivate the AIDS virus and to deliver anti-tumor drugs to tumor sites for the treatment of cancer. Subsequent commercialization will include the development of therapies for other viral diseases and the preparation of detoxification agents. The therapeutic catalytic antibodies to antigens derived from these haptens. A new approach to the design of these haptens involves the use of aminophosphinic acids and is based on an analysis of enzyme mechanisms.