RADIOGRAPHIC AID TO PROTON THERAPY

质子治疗的射线照相辅助

• 批准号: 3492539
• 负责人: RONALD L MARTIN
• 金额: $ 5万
• 依托单位: ACCTEK ASSOCIATES, INC.
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-04-01 至 1991-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3492539
• 关键词: clinical biomedical equipment; monitoring device; neoplasm /cancer radiation therapy; particle beam; proton beam; radiography

The long-term objective of this program is the development of the capability of precision proton radiography with accelerator systems designed or used for proton radiation therapy. A proton radiograph taken immediately prior to radiation treatment could give increased confidence in the adequacy of the treatment plan, check alignment with tumor site, and confirm readiness and calibration of the entire system. For this result raster scanning of a very high quality proton beam is required, and the implementation has the potential of improving the effectiveness of radiation treatment of cancer by protons. Its use for diagnostic purposes independent of therapy could be justified in some instances. The specific aims of Phase I would be to demonstrate on a 200 MeV proton beam using ACCTEK's raster scanning system the practical feasibility of proton radiography and to evaluate its potential, as well as computed tomography, as an adjunct to proton therapy and for independent diagnostic purposes. Phase II would develop and test commercial systems including detectors and computer analysis programs. Phase III, funded privately would provide the equipment and techniques to implement this capability at any of the proton therapy facilities under construction or to be constructed.

这项计划的长期目标是发展 利用加速器系统进行精密质子照相的能力 设计或用于质子放射治疗。拍下的一张质子射线照片 在接受放射治疗之前可能会增加对 治疗计划的充分性，检查与肿瘤部位的一致性，以及 确认整个系统的就绪性和校准。对于这一结果 需要对非常高质量的质子束进行栅格扫描，并且 实施有可能提高 质子放射治疗癌症。它用于诊断目的 在某些情况下，不依赖于治疗是合理的。 第一阶段的具体目标是演示一个200 MeV的质子 射束采用ACCTEK的栅格扫描系统的实用可行性 质子射线照相和评估其潜力，以及计算 体层摄影术作为质子治疗和独立诊断的辅助手段 目的。第二阶段将开发和测试商业系统，包括 探测器和计算机分析程序。第三阶段，私人资助 将提供实现这一能力的设备和技术 任何在建或即将建设的质子治疗设施 建造的。