PROTON ACCELERATOR FOR MEDICAL APPLICATIONS

医疗应用质子加速器

• 批准号: 3506470
• 负责人: RONALD L MARTIN
• 金额: $ 32.71万
• 依托单位: ACCTEK ASSOCIATES, INC.
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-09-15 至 1989-09-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3506470
• 关键词: biomedical equipment development; clinical biomedical equipment; controlled environment chamber; health economics; magnetism; neoplasm /cancer radiation therapy; particle accelerators; proton beam

The long range goal of this program is the development and commercialization of proton accelerators suitable for radiation therapy of cancer in hospital or clinical settings. These can provide beams of protons up to 60 nA at 250 MeV in a smaller version of the accelerator. A larger version will produce helium ions to 250 MeVmu, or with lower magnetic field, 250 MeV protons form H- acceleration and charge exchange extraction for precision current control. The later could make the use of raster scanning beams of protons for dose delivery to the patient possible, with significant implications in reducing the size and cost of the gantry and the potential for significantly improved radiation treatment. The Phase I effort completed the conceptual design and cost estimate for these accelerators. The Phase II program would construct models of the magnets designed, assemble them in a section of a ring, and conduct a series of experimental demonstrations with H- beam injected from a 300 KeV preaccelerator, including simulated charge exchange extraction with feedback current control. These would demonstrate the commercial feasibility of the design concepts. Phase III, supported privately, would make commercial units available.

该计划的长期目标是发展和 适用于辐射的质子加速器的商业化 在医院或临床环境中的癌症治疗。 这些可以 在一个更小的空间中提供高达60 nA的250 MeV质子束， 加速器的版本 一个更大的版本将产生氦 离子到250 MeVmu，或用较低的磁场，250 MeV 质子形成H-加速和电荷交换提取， 精密电流控制 后者可以利用光栅 扫描质子束以向患者进行剂量输送 可能的，具有重大影响，在减少规模和 门架的成本和显着改善的潜力 放射治疗 第一阶段的工作完成了概念设计和成本 对这些加速器的估计。 第二阶段计划将 构建设计的磁体模型，将其组装在 环的一部分，并进行了一系列的实验 用300千电子伏的H束注入的演示 预加速器，包括模拟电荷交换提取 具有反馈电流控制。 这些将证明该设计的商业可行性 理念的 第三阶段由私人支持， 单位可用。