PROTON ACCELERATOR FOR MEDICAL APPLICATIONS

医疗应用质子加速器

• 批准号: 3506471
• 负责人: RONALD L MARTIN
• 金额: $ 17.26万
• 依托单位: ACCTEK ASSOCIATES, INC.
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-09-15 至 1989-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3506471
• 关键词: biomedical equipment development; clinical biomedical equipment; controlled environment chamber; health economics; magnetism; neoplasm /cancer radiation therapy; particle accelerators; proton beam

The long range goal of this program is the development and commercialization of proton accelerators suitable for radiation therapy of cancer in hospital or clinical settings. These can provide beams of protons up to 60 nA at 250 MeV in a smaller version of the accelerator. A larger version will produce helium ions to 250 MeVmu, or with lower magnetic field, 250 MeV protons form H- acceleration and charge exchange extraction for precision current control. The later could make the use of raster scanning beams of protons for dose delivery to the patient possible, with significant implications in reducing the size and cost of the gantry and the potential for significantly improved radiation treatment. The Phase I effort completed the conceptual design and cost estimate for these accelerators. The Phase II program would construct models of the magnets designed, assemble them in a section of a ring, and conduct a series of experimental demonstrations with H- beam injected from a 300 KeV preaccelerator, including simulated charge exchange extraction with feedback current control. These would demonstrate the commercial feasibility of the design concepts. Phase III, supported privately, would make commercial units available.

这项计划的长远目标是发展和 适用于辐射的质子加速器的商业化 在医院或临床环境中治疗癌症。这些可以 在250 MeV下提供高达60 nA的质子束 加速器的版本。一个更大的版本将产生氦 离子强度为250 MeVu，或磁场较低时为250 MeV 质子的氢加速和电荷交换引出 精确的电流控制。后者可以利用栅格 扫描质子束以向患者提供剂量 可能的，对减少大小和 龙门架的成本和显著改进的潜力 放射治疗。 第一阶段工作完成了概念设计和成本 对这些加速器的估计。第二阶段计划将 构建设计的磁铁模型，将它们组装在一个 一段环，并进行了一系列的实验 从300keV注入H束的演示 预加速器，包括模拟电荷交换提取 具有反馈电流控制。 这些都将证明设计的商业可行性。 概念。第三阶段，由私人支持，将使商业 单位可用。