Closed-loop deep brain stimulation: Optimising treatment of Parkinson’s disease using adaptive stimulation

闭环深部脑刺激：使用适应性刺激优化帕金森病的治疗

• 批准号: nhmrc : 1103238
• 负责人: Dr Arthur Thevathasan
• 金额: $ 49.9万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/closed-loop-deep-adaptive-stimulation/662662
• 关键词: Closed; loop; deep; brain; stimulation

Deep brain stimulation is an established therapy for Parkinson's disease when patients’ symptoms cannot be controlled adequately using medication. Although deep brain stimulation usually improves quality of life significantly, existing devices have shortcomings that often result in poor symptom alleviation and/or undesirable side-effects. This project is aimed at developing an innovative system that automatically adjusts stimulation according to the continually fluctuating needs of each patient.

脑深部电刺激是一种治疗帕金森病的既定疗法，当患者的症状不能充分控制使用药物。尽管脑深部刺激通常显著改善生活质量，但现有设备具有通常导致不良症状缓解和/或不期望的副作用的缺点。该项目旨在开发一种创新系统，根据每位患者不断波动的需求自动调整刺激。