Clarifying the clinical application and mechanisms of pedunculopontine nucleus deep brain stimulation for Parkinson’s disease

阐明桥脚核脑深部电刺激治疗帕金森病的临床应用及机制

• 批准号: nhmrc : 1066565
• 负责人: Dr Arthur Thevathasan
• 金额: $ 13.49万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/clarifying-clinical-application-parkinsons-disease/455247
• 关键词: Clarifying; clinical; application; mechanisms; pedunculopontine

Over 64,000 Australians have Parkinson’s disease. Most patients with Parkinson’s disease ultimately develop gait ‘freezing’ and poor balance, which impair quality of life and cause falls. Unfortunately, gait freezing and poor balance often don’t improve with conventional treatments. We are therefore helping to develop a new treatment for these symptoms, which involves implanting a pacemaker into a very deep region in the brain called the “Pedunculopontine Nucleus’.

超过6.4万澳大利亚人患有帕金森病。大多数帕金森氏症患者最终会出现步态“冻结”和平衡能力差，从而影响生活质量并导致跌倒。不幸的是，步态冻结和平衡能力差通常不能通过常规治疗得到改善。因此，我们正在帮助开发一种新的治疗这些症状的方法，其中包括在大脑深处被称为“桥脚核”的区域植入一个起搏器。