BIOMEDICAL RESEARCH ON CORAL REEF ORGANISMS OF GUAM

拟议的关岛大学海洋实验室的总体目标 关岛珊瑚礁生物医学研究MBRS计划 为教师和有才华的少数族裔学生提供机会 利用生态系统进行具有生物医学意义的研究 关岛和西部丰富多样的热带海洋环境 太平洋。该提案包括三个研究项目，由 定期首席调查人员，由一个 助理调查员，以及结构良好的浓缩组成部分。这个 First Proposal将继续寻求更好地了解 热带地区普遍存在的雪卡毒素鱼中毒问题，包括 关岛。具体地说，这项研究将检查 底栖甲藻冈比亚毒素，其微生境专一性， 季节性和种群动态。第二个项目将涉及 青岛市居民病原菌流行与分布研究 关岛周围的沉积物和礁石栖息地。第三个项目将研究 珊瑚生殖生物学，重点是遗传机制。 最后，一个副研究员项目将专注于生物医学 珊瑚礁无脊椎动物体内的活性天然产物。 通过建议的活动，学生和教职员工研究 环境将得到改善。参与研究的教职员工和学生 活动将与美国本土的科学家互动，他们将 有机会通过以下方式学习新技术和发展 参加校外会议和研究活动，以及 校园研讨会、工作坊和非正式讨论，通过访问 科学家。在地理上与世隔绝的关岛， 经验对学生在做决策时特别有价值 关于研究生的职业生涯。

The general objective of the proposed University of Guam Marine Laboratory MBRS program, Biomedical Research on Coral-Reef Organisms of Guam, is to provide opportunities for the faculty and talented minority students to conduct biomedically significant research utilizing the ecologically diverse and rich tropical marine environment of Guam and the western Pacific. The proposal includes three research projects submitted by regular principal investigators, a research project submitted by an associate investigator, and a well-structured enrichment component. The first proposal will continue the search for a better understanding of the ciguatera fish-poisoning problem that is prevalent in the tropics including Guam. Specifically, this research will examine the distribution of the benthic dinoflagellate Gambierdiscus toxicus, its microhabitat specificity, seasonality, and population dynamics. The second project will involve studies of the prevalence and distribution of pathogenic bacteria in sediments and reef habitats around Guam. The third project will study reproductive biology of corals with an emphasis on genetic mechanisms. Finally, an associate investigator project will focus on biomedically active natural products in coral-reef invertebrates. Through the proposed activities, the student and faculty research environment will be enhanced. Faculty and students involved in research activities will interact with scientists in the mainland U.S. and they will have the opportunity to learn new techniques and developments by participating in off-campus conferences and research activities as well as on-campus seminars, workshops, and informal discussions by visiting scientists. In the geographically isolated location of Guam, such experiences are especially valuable to the students when making decisions on postgraduate careers.