Colonic dysmotility is a significant aetiological factor in faecal incontinence
Colonic dysmotility is a significant aetiological factor in faecal incontinence
批准号:
nhmrc : GNT1162223
负责人:
金额:
$42.23万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2019
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2019-01-01 至 --
中文摘要
大便失禁是令人尴尬的,可能会破坏病人的生活质量。肛门括约肌在控制排便中起着重要作用,但患者可以有正常的括约肌功能,但仍会出现严重的尿失禁。在这个项目中,我们将使用我们独特的记录技术来识别这些患者的远端结肠收缩性异常区域,并表明这有助于失禁。这些数据将为治疗提供一个新的目标区域。
英文摘要
Faecal incontinence is embarrassing and can ruin a patient’s quality of life. While the anal sphincters play an important role in controlling defaecation, patients can have normal sphincter function and still suffer severe incontinence. In this project we will use our unique recording techniques to identify an abnormal region of contractility in the distal colon of these patients and show that this contributes to the incontinence. These data will provide a new targeted region for treatment.
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