Combined TMS-EEG for early diagnosis of Alzheimer’s disease

TMS-EEG 联合用于阿尔茨海默病的早期诊断

• 批准号: nhmrc : 1102272
• 金额: $ 41.37万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Targeted Calls
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/combined-tms-eeg-alzheimers-disease/662596
• 关键词: Combined; TMS; EEG; early; diagnosis

Early diagnosis of Alzheimer's disease is key to more effective early intervention. Current biomarkers are expensive and are not suited for detecting the subtle changes in brain function that occur during the initial stages of the disease. Non-invasive brain stimulation is pain-free and inexpensive, and can directly probe brain function in conscious humans. This project will investigate whether these techniques might be used to identify markers of early brain dysfunction in Alzheimer’s disease.

阿尔茨海默病的早期诊断是更有效的早期干预的关键。目前的生物标记物价格昂贵，不适合检测在疾病初期发生的大脑功能的细微变化。非侵入性脑刺激是无痛且廉价的，并且可以直接探测有意识的人类的大脑功能。该项目将研究这些技术是否可以用于识别阿尔茨海默病早期脑功能障碍的标志物。