EXPANSION OF THE PEDIATRIC AIDS CLINICAL TRIAL GROUP

这是一个已经存在的、功能强大的跨学科 致力于医疗保健、临床和医疗服务的多中心专家联盟 以及与儿童艾滋病毒感染有关的基础研究(PAID)和 怀孕的女人。这个位于布朗克斯的网络的成员包括医疗保健 专业人士、生物统计学家、药理学家和科学家 儿科、免疫学、传染病、微生物学、 分子生物学和遗传学。该网络有效地覆盖了布朗克斯 全国最大的儿科艾滋病中心。这是第一个也是 美国最大的PAID中心&GT；预计将有新的儿科艾滋病毒感染者 该财团地理集水区的新生儿也是 最大的，超过4%的脐带血艾滋病毒抗体阳性。 该小组的成员在成人ATEU试验和 在AECOM设计的儿科治疗。一种儿科的发展 ACTG将补充我们现有的努力，使我们能够包括成年人 和同一个HIV感染家庭的儿科成员进行治疗 审判。这种以艾滋病家庭为导向的方法提高了入学人数和 长期合规。 阿尔伯特·爱因斯坦医学院合作治疗小组 将与NIH ACTGs互动，以促进旨在设计的研究 在免疫重建领域的新的治疗方法， 抗艾滋病毒药物和艾滋病毒相关疾病的治疗试验。

This is an already existing and functional interdisciplinary multicentered consortium of experts dedicated to health care, clinical as well as basic research related to HIV infection in children (PAIDS) and pregnant women. Members of this Bronx based network include health care professionals, biostatisticians, pharmacologists, and scientists in the filed of pediatrics, immunology, infectious diseases, microbiology, molecular biology and genetics. The network effectively covers the Bronx the largest epicenter of pediatrics AIDS nationwide. It is the first and largest PAIDS center in the USA> The projected new pediatric HIV infected newborns in the geographic catchment area of the consortium is also the largest, with over 4% of all cord bloods being HIV antibody positive. Members of the group have gained experience in adult ATEU trials and in pediatric treatments designed at AECOM. The development of a pediatric ACTG will complement our existing efforts by enabling us to include adult and pediatric members of the same HIV infected family in therapeutic trials. Such an AIDS Family oriented approach has improved enrollment and longterm compliance. The Albert Einstein College of Medicine PAIDS Cooperative Treatment Group will interact with the NIH ACTGs to foster research aimed at the design of novel therapeutic approaches in the areas of immune reconstitution, anti-HIV agents and treatment trials for HIV related diseases.