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THE ROLE OF CELL MEMBRANE STRUCTURE IN CELLULAR RECOGNITION

THE ROLE OF CELL MEMBRANE STRUCTURE IN CELLULAR RECOGNITION
细胞膜结构在细胞识别中的作用
批准号：
3823149
负责人：
W H ADLER
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE ON AGING
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3823149
关键词：
AIDS T lymphocyte aging animal age group animal old age burns cell membrane cell population study cellular immunity cytotoxicity dialysis therapy flow cytometry hormone regulation /control mechanism human subject human tissue immunodeficiency immunoregulation interferons juvenile animal lymphocyte membrane structure monoclonal antibody nosocomial infections nursing homes phagocytosis renal failure spleen tissue /cell culture zinc

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中文摘要
翻译
艾滋病患者、烧伤患者、肾脏病患者免疫缺陷的调查
英文摘要
Investigation of immunodeficiencies in AIDS patients, burn patients, renal dialysis patients and infections in nursing home residents, along with basic studies on cellular recognition by mouse T cells and pulmonary lavage cells has resulted in the following insights. Macrophage/monocyte recognition of antigen proceeds through Fc receptor binding of specific antibody. The function can be boosted by interferon and is deficient in patients with AIDS. Burn patients have endotoxemia induced NK cell functional abnormalities. Dialysis patients have evidence of chronic viral infections, especially if they have been transfused. T cell recognition of alloantigen requires the participation of the target cell in initiating the activation of the T cell.
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THE ROLE OF CELL MEMBRANE STRUCTURE IN CELLULAR RECOGNITION
  • 批准号：
    3767761
  • 项目类别：
  • 资助金额：
    $0.0万
  • 财政年份：
    --
  • 负责人：
    W H ADLER
  • 依托单位：
    NATIONAL INSTITUTE ON AGING
HOST FACTORS RELATING TO HIV INFECTIONS
  • 批准号：
    3767820
  • 项目类别：
  • 资助金额：
    $0.0万
  • 财政年份：
    --
  • 负责人：
    W H ADLER
  • 依托单位：
    NATIONAL INSTITUTE ON AGING
CLINICAL IMMUNE SURVEY OF THE LONGITUDINAL PROJECT PARTICIPANTS
  • 批准号：
    5200274
  • 项目类别：
  • 资助金额：
    $0.0万
  • 财政年份：
    --
  • 负责人：
    W H ADLER
  • 依托单位：
    NATIONAL INSTITUTE ON AGING
THE ROLE OF CELL MEMBRANE STRUCTURES ON CELLULAR RECOGNITION
  • 批准号：
    5200272
  • 项目类别：
  • 资助金额：
    $0.0万
  • 财政年份：
    --
  • 负责人：
    W H ADLER
  • 依托单位：
    NATIONAL INSTITUTE ON AGING
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