CENTRALIZED CHEMOPREVENTIVE AGENT REPOSITORY

该项目将建立一个集中的代理来源，用于 的化学预防计划进行的临床前和临床研究 国家癌症研究所(NCI)。对于临床前研究，该项目 将提供：购买散装试剂化学物质；收到 来自供应商的代理商；安全稳定的储存；重新包装代理商以满足 用户需求；以及向用户发运适当的代理 表征数据和操作说明。对于供应商；安全和 稳定储存；根据需要为剂量配方提供行政支持， 包装、日历包装和标签，包括发货给NCI 如有需要，指定承建商完成这些工作；以及 运往最终目的地的货物。总体上的基本活动 操作包括：监测用户地点的库存水平；库存 控制以确保及时重新订购和运送代理；维护 最新的发货记录；以及有限的质量保证 散装药剂的保质期和纯度等性能。

This project would establish a centralized source of agents for use in preclinical and clinical studies by the chemoprevention program of the National Cancer Institute (NCI). For preclinical studies, the project would provide: purchase of bulk reagent chemical substances; receipt of agents from suppliers; safe and stable storage; repacking agents to meet user needs; and shipment of agents to users with appropriate characterization data and handling instructions. For suppliers; safe and stable storage; administrative support as needed for dosage formulation, encapsulation, calendar packing and labeling, including shipment to NCI designated contractors to accomplish these tasks if necessary; and shipment to final destination. Essential activities for the overall operation include: monitoring stock levels at user locations; inventory control to ensure timely reordering, and shipping of agents; maintenance of up-to-date records of shipments; and limited quality assurance capability such as shelf life and purity of bulk agents.