A National Research Facility for EPR Spectroscopy, 2022-2027

国家 EPR 光谱研究设施，2022-2027

• 批准号: EP/W014521/1
• 负责人: David Collison
• 金额: $ 630.88万
• 依托单位: University of Manchester
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FW014521%2F1
• 关键词: National; Research; Facility; EPR; Spectroscopy

Electrons are fundamental to the composition of all materials, determining the structure of molecular bonds and the stability and properties of compounds. The study of the electronic distribution in molecules therefore provides a direct window into understanding molecular structure, function and bonding. Electrons possess a fundamental property called "spin", which, pictured classically causes the electron to behave as a bar-magnet when placed in a magnetic field. In many materials all electrons are present in pairs, with the spin on the two electrons being equal and opposite. However, in many important materials there are unpaired electrons: such materials are called paramagnets. Paramagnets are ubiquitous across physical, biological and materials sciences, for example in free-radicals, metal ions, active sites in biological systems, or defects in solids, and these unpaired electrons are critical in dictating the electronic, magnetic and (bio)chemical behaviour of such materials. Unpaired electrons can be intrinsic to the material or extrinsic, induced by, for example, chemical doping or labelling, or by electrochemical or optical excitation.The most powerful method to study paramagnetic materials is Electron Paramagnetic Resonance (EPR) spectroscopy, also known as Electron Spin Resonance (ESR), part of the magnetic resonance range of techniques that also includes Magnetic Resonance Imaging (MRI) and Nuclear Magnetic Resonance (NMR). EPR directly probes the environment of the unpaired electrons, yielding information on the chemical environment in which the electron is present. State-of-the-art EPR requires substantial instrumentation, including continuous wave and pulsed techniques (differing in how microwaves are applied, and how the signal is detected), and variable magnetic field and temperature regimes, giving access to different information content on the paramagnet. A National Research Facility (NRF) for EPR gives a cost-effective method for wide access to infrastructure, expertise and training to the UK academic community. The NRF will support researchers in their projects from first enquiry, where assistance can be provided to design, plan and cost experiments into grant applications, through to training via hands-on experience and training courses, support to perform experiments, and advice and expertise to aid data analysis, modelling and interpretation.

电子是所有材料组成的基础，确定分子键的结构以及化合物的稳定性和性能。因此，对分子中电子分布的研究为理解分子结构，功能和键合提供了直接的窗口。电子具有称为“旋转”的基本特性，该特性经典地使电子在放置在磁场中时作为条形磁铁行为。在许多材料中，所有电子都成对存在，两个电子上的自旋相等且相反。但是，在许多重要的材料中，有未配对的电子：此类材料称为Paramagnets。 Paramagnet在物理，生物学和材料科学方面无处不在，例如在自由基，金属离子，生物系统中的活性位点或固体缺陷中，这些未配对的电子对于指示这些材料的电子，磁性和（生物）化学行为至关重要。 Unpaired electrons can be intrinsic to the material or extrinsic, induced by, for example, chemical doping or labelling, or by electrochemical or optical excitation.The most powerful method to study paramagnetic materials is Electron Paramagnetic Resonance (EPR) spectroscopy, also known as Electron Spin Resonance (ESR), part of the magnetic resonance range of techniques that also includes Magnetic Resonance Imaging (MRI) and Nuclear磁共振（NMR）。 EPR直接探测未配对电子的环境，从而获得有关存在电子的化学环境的信息。最先进的EPR需要实质性的仪器，包括连续波和脉冲技术（应用微波的应用方式以及检测到信号的方式不同），以及可变的磁场和温度状态，从而可以访问Paramagnet上的不同信息内容。 EPR的国家研究机构（NRF）提供了一种具有成本效益的方法，可为英国学术界广泛获得基础设施，专业知识和培训。 NRF将从第一次询问开始支持研究人员的项目，在该项目中，可以为赠款申请设计，计划和成本实验提供帮助，直到通过动手经验和培训课程进行培训，提供实验的支持以及建议和专业知识，以帮助数据分析，建模和解释。

项目成果

Decorating beads with paramagnetic rings: synthesis of inorganic-organic [10^14]rotaxanes as shown by spin counting

用顺磁环装饰珠子：通过自旋计数显示无机-有机[10^14]轮烷的合成

• DOI: 10.26434/chemrxiv-2022-w6g7w
• 发表时间: 2022
• 作者: Asthana D

Hexanuclear Ln6 L6 Complex Formation by Using an Unsymmetric Ligand.

使用不对称配体形成六核 Ln6 L6 络合物。

• DOI: 10.1002/chem.202302497
• 发表时间: 2023
• 期刊: Chemistry (Weinheim an der Bergstrasse, Germany)
• 作者: Bell DJ

Erythrosin B as a New Photoswitchable Spin Label for Light-Induced Pulsed EPR Dipolar Spectroscopy.

• DOI: 10.3390/molecules27217526
• 发表时间: 2022-11-03
• 期刊: MOLECULES
• 影响因子: 4.6
• 作者: Bertran, Arnau;Morbiato, Laura;Aquilia, Sara;Gabbatore, Laura;De Zotti, Marta;Timmel, Christiane R.;Di Valentin, Marilena;Bowen, Alice M.
• 通讯作者: Bowen, Alice M.

Direct Comparison between Förster Resonance Energy Transfer and Light-Induced Triplet-Triplet Electron Resonance Spectroscopy.

福斯特共振能量转移与光诱导三重态-三重态电子共振光谱的直接比较。

• DOI: 10.1021/jacs.3c04685
• 发表时间: 2023-10-25
• 期刊: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
• 影响因子: 15
• 作者: Bertran, Arnau;Morbiato, Laura;Sawyer, Jack;Dalla Torre, Chiara;Heyes, Derren J.;Hay, Sam;Timmel, Christiane R.;Di Valentin, Marilena;De Zotti, Marta;Bowen, Alice M.
• 通讯作者: Bowen, Alice M.