A National Research Facility for EPR Spectroscopy, 2022-2027

国家 EPR 光谱研究设施，2022-2027

• 批准号: EP/W014521/1
• 负责人: David Collison
• 金额: $ 630.88万
• 依托单位: University of Manchester
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FW014521%2F1
• 关键词: National; Research; Facility; EPR; Spectroscopy

Electrons are fundamental to the composition of all materials, determining the structure of molecular bonds and the stability and properties of compounds. The study of the electronic distribution in molecules therefore provides a direct window into understanding molecular structure, function and bonding. Electrons possess a fundamental property called "spin", which, pictured classically causes the electron to behave as a bar-magnet when placed in a magnetic field. In many materials all electrons are present in pairs, with the spin on the two electrons being equal and opposite. However, in many important materials there are unpaired electrons: such materials are called paramagnets. Paramagnets are ubiquitous across physical, biological and materials sciences, for example in free-radicals, metal ions, active sites in biological systems, or defects in solids, and these unpaired electrons are critical in dictating the electronic, magnetic and (bio)chemical behaviour of such materials. Unpaired electrons can be intrinsic to the material or extrinsic, induced by, for example, chemical doping or labelling, or by electrochemical or optical excitation.The most powerful method to study paramagnetic materials is Electron Paramagnetic Resonance (EPR) spectroscopy, also known as Electron Spin Resonance (ESR), part of the magnetic resonance range of techniques that also includes Magnetic Resonance Imaging (MRI) and Nuclear Magnetic Resonance (NMR). EPR directly probes the environment of the unpaired electrons, yielding information on the chemical environment in which the electron is present. State-of-the-art EPR requires substantial instrumentation, including continuous wave and pulsed techniques (differing in how microwaves are applied, and how the signal is detected), and variable magnetic field and temperature regimes, giving access to different information content on the paramagnet. A National Research Facility (NRF) for EPR gives a cost-effective method for wide access to infrastructure, expertise and training to the UK academic community. The NRF will support researchers in their projects from first enquiry, where assistance can be provided to design, plan and cost experiments into grant applications, through to training via hands-on experience and training courses, support to perform experiments, and advice and expertise to aid data analysis, modelling and interpretation.

电子是所有材料组成的基础，决定了分子键的结构以及化合物的稳定性和性质。因此，对分子中电子分布的研究为理解分子结构、功能和成键提供了一个直接的窗口。电子具有一种称为“自旋”的基本性质，经典的描述是，当电子被置于磁场中时，它的行为就像一个条形磁铁。在许多材料中，所有电子都成对存在，两个电子的自旋相等且相反。然而，在许多重要的材料中存在未成对电子：这种材料被称为顺磁体。顺磁体在物理、生物和材料科学中无处不在，例如在自由基、金属离子、生物系统中的活性位点或固体中的缺陷中，这些未成对电子在决定这些材料的电子、磁性和（生物）化学行为方面至关重要。不成对电子可以是材料固有的，也可以是外部的，例如通过化学掺杂或标记，或者通过电化学或光学激发来诱导。研究顺磁材料的最有力的方法是电子顺磁共振（EPR）光谱，也称为电子自旋共振（ESR），磁共振技术的一部分，还包括磁共振成像（MRI）和核磁共振（NMR）。EPR直接探测未成对电子的环境，产生关于电子存在的化学环境的信息。最先进的EPR需要大量的仪器，包括连续波和脉冲技术（不同的是如何应用微波，以及如何检测信号），以及可变的磁场和温度制度，从而获得顺磁体上的不同信息内容。EPR的国家研究设施（NRF）为英国学术界提供了一种具有成本效益的方法，可以广泛获得基础设施，专业知识和培训。NRF将支持研究人员的项目，从第一次调查，在那里可以提供援助，以设计，计划和成本实验到赠款申请，通过实践经验和培训课程的培训，支持进行实验，并提供咨询和专业知识，以帮助数据分析，建模和解释。

项目成果

Decorating beads with paramagnetic rings: synthesis of inorganic-organic [10^14]rotaxanes as shown by spin counting

用顺磁环装饰珠子：通过自旋计数显示无机-有机[10^14]轮烷的合成

• DOI: 10.26434/chemrxiv-2022-w6g7w
• 发表时间: 2022
• 作者: Asthana D

Hexanuclear Ln6 L6 Complex Formation by Using an Unsymmetric Ligand.

使用不对称配体形成六核 Ln6 L6 络合物。

• DOI: 10.1002/chem.202302497
• 发表时间: 2023
• 期刊: Chemistry (Weinheim an der Bergstrasse, Germany)
• 作者: Bell DJ

Direct Comparison between Förster Resonance Energy Transfer and Light-Induced Triplet-Triplet Electron Resonance Spectroscopy.

福斯特共振能量转移与光诱导三重态-三重态电子共振光谱的直接比较。

• DOI: 10.1021/jacs.3c04685
• 发表时间: 2023-10-25
• 期刊: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
• 影响因子: 15
• 作者: Bertran, Arnau;Morbiato, Laura;Sawyer, Jack;Dalla Torre, Chiara;Heyes, Derren J.;Hay, Sam;Timmel, Christiane R.;Di Valentin, Marilena;De Zotti, Marta;Bowen, Alice M.
• 通讯作者: Bowen, Alice M.

Erythrosin B as a New Photoswitchable Spin Label for Light-Induced Pulsed EPR Dipolar Spectroscopy.

• DOI: 10.3390/molecules27217526
• 发表时间: 2022-11-03
• 期刊: MOLECULES
• 影响因子: 4.6
• 作者: Bertran, Arnau;Morbiato, Laura;Aquilia, Sara;Gabbatore, Laura;De Zotti, Marta;Timmel, Christiane R.;Di Valentin, Marilena;Bowen, Alice M.
• 通讯作者: Bowen, Alice M.