INVESTIGATION OF SELECTED PATIENT GROUPS FROM THE CSSCD

承包商应作为临床研究中心， 从镰状细胞病合作研究中选择的患者组 （CSSCD）。 承包商应与CSSCD的其他调查人员合作 和NHLBI工作人员在制定和实施一项议定书， 继续随访新生儿队列和存活超过年龄的患者 三十五岁 本合同的主要目的是继续 随访目前在CSSCD中随访的新生儿患者队列 为了更好地了解早期器官损伤的严重程度、发病情况和风险， 导致某些并发症和结果的因素。 本研究 还打算跟踪另一个重要的存活患者队列， 超过35岁，以更好地了解寿命和死亡原因。

The Contractor shall serve as a clinical center for the investigation of selected patient groups from the Cooperative Study of Sickle Cell Disease (CSSCD). The Contractor shall collaborate with other CSSCD investigators and NHLBI staff in the development and implementation of a protocol to continue to follow the newborn cohort and patients surviving beyond age thirty-five. The principal objective of this contract is to continue to follow the newborn cohort of patients presently being followed in the CSSCD to better understand severity, onset of early organ damage, and risk factors contributing to certain complications and outcome. This study is also intended to follow another important cohort of patients surviving beyond age thirty-five to better understand longevity and causes of death.