INVESTIGATION OF SELECTED PATIENT GROUPS FROM THE CSSCD

承包人应作为临床中心，以调查 从镰刀细胞病的合作研究中选择的患者组 (CSSCD)。承包商应与CSSCD其他调查人员合作 和NHLBI工作人员一起开发和实施一项协议，以 继续跟踪新生儿队列和超过年龄存活的患者 三十五岁。本合同的主要目标是继续 跟踪目前在CSSCD中接受随访的新生儿队列患者 为了更好地了解严重程度、早期器官损害的发病情况和风险 导致某些并发症和结果的因素。这项研究是 也打算跟踪另一组重要的幸存患者 超过35岁，以更好地了解长寿和死亡原因。

The Contractor shall serve as a clinical center for the investigation of selected patient groups from the Cooperative Study of Sickle Cell Disease (CSSCD). The Contractor shall collaborate with other CSSCD investigators and NHLBI staff in the development and implementation of a protocol to continue to follow the newborn cohort and patients surviving beyond age thirty-five. The principal objective of this contract is to continue to follow the newborn cohort of patients presently being followed in the CSSCD to better understand severity, onset of early organ damage, and risk factors contributing to certain complications and outcome. This study is also intended to follow another important cohort of patients surviving beyond age thirty-five to better understand longevity and causes of death.