心肌梗塞溶栓的临床试验-猫眼课题宝

心肌梗塞溶栓的临床试验

批准号：

3660130

负责人：

ALLAN M ROSS

金额：

$7.04万

依托单位：

GEORGE WASHINGTON UNIVERSITY

依托单位国家：

美国

项目类别：

财政年份：

1983

资助国家：

美国

项目状态：

已结题

起止时间：

1983-06-30 至 1988-09-30

来源：

https://reporter.nih.gov/project-details/3660130

关键词：

cardiotonic agents cooperative study coronary vasodilator drug administration routes drug adverse effect fibrinolytic agents fibrinolytic therapy heart imaging /visualization /scanning heart motion human subject human therapy evaluation intracardiac volume myocardial infarct sizing myocardial infarction nitroglycerin radionuclide diagnosis

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中文摘要

翻译

评估溶栓剂在减小梗死面积和减少梗死面积方面的疗效

英文摘要

Assess the efficacy of a thrombolytic agent in reducing infarct size and thereby improving ventricular function and subsequent morbidity and mortality. The primary endpoint will be total mortality during the follow up period. Secondary endpoints include determination of the: effect of thrombolytic therapy on left ventricular ejection fraction;proportion of patients suspected of having myocardial infarction with complete versus incomplete occlusion of the infarct related artery; time limits for successful reperfusion including differences according to the route of administration; and frequency and severity of adverse effects of intracoronary and intravenous administration of thrombolytic agents in patients with acute infarction.

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