The Evolution of stripe rust virulence

条锈病毒力的演变

• 批准号: DE150101897
• 负责人: A/Prof Benjamin Schwessinger
• 金额: $ 23.53万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-09-30 至 2018-09-29
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE150101897
• 关键词: Evolution; stripe; rust; virulence

Fungal crop pathogen epidemics lead to severe yield losses worldwide, impact national economies and individual human lives. Wheat stripe rust fungal epidemics caused by new virulent races can lead to 80 per cent reduction in yield. This project aims to investigate the molecular mechanisms leading to newly virulent races by whole genome, epigenome and transcriptome comparison of several wheat stripe rust races. This project aims to fundamentally advance our understanding of evolutionary forces driving virulence and specification at the whole (epi-)genome level in important fungal crop pathogens. This will promote new crop protection strategies important for local and global food security in an ever-changing environment.

真菌性作物病原体的流行在世界范围内导致严重的产量损失，影响国家经济和个人生活。由新的毒性小种引起的小麦条锈病真菌流行可导致产量减少80%。本项目旨在通过对几个小麦条锈菌小种的全基因组、表观基因组和转录组的比较研究，探讨产生新致病小种的分子机制。该项目旨在从根本上推进我们对重要真菌作物病原体在全（表观）基因组水平上驱动毒力和特异性的进化力量的理解。这将促进新的作物保护战略，对不断变化的环境中的地方和全球粮食安全至关重要。