MAGNetic sensing microsystem for InjectABLE magnetomyography

尽管经过了几十年的研究，但对于控制灵巧假肢的直观和生理上适当的人机界面（HMI）的追求还远远没有完成。目前，世界各国研究人员的重点是利用骨骼肌肉产生的“电场”进行人机交互。近年来，研究的重点转移到测量肌肉纤维中离子电流产生的“磁场”，即磁肌图（MMG）。由于磁场不受组织体积导电性的影响，MMG有可能以高空间分辨率提供有关肌肉收缩的额外信息。目前用于MMG记录的传感系统存在信噪比差、受地磁场和周围环境背景噪声影响大的问题。为了解决这个问题，这个项目探索了一个强大的和高灵敏度的传感微系统的开发，用于使用磁传感器进行MMG记录。开发一种具有背景校准和自动可编程灵敏度的信号调理装置，以有效补偿不良磁场的影响。此外，将展示一个概念验证原型，用于亚毫米横截面的MMG记录，适合使用导管在肌肉表面注射。这个项目非常及时，因为人机界面的发展是一个新兴的领域，未来非常有希望。

Despite several decades of research, the quest for an intuitive and physiologically appropriate human-machine interface (HMI) for the control of dexterous prostheses is far from being completed. The focus of the researchers around the world so far is on use of "Electric field" generated by the skeleton muscles for HMI. Recently, focus of the research is shifted toward measurement of "Magnetic field" generated by the ionic current flowing in muscle fiber - called as Magnetomyogram (MMG). The MMG has the potential to provide additional information about the muscle contraction with high spatial resolution since the magnetic field is not affected by the volume conductive property of tissues. The current sensing systems for MMG recording suffers from poor SNR and highly affected by the earth magnetic field and background noises in the surrounding environment. To address this, this project explores the development of a robust and highly sensitive sensing microsystem for MMG recording using magnetic sensors. It will develop a signal conditioning unit with background calibration and auto-programmable sensitivity to effectively compensate the effects of undesirable magnetic field. In addition, a proof-of-concept prototype will be demonstrated for MMG recording with a sub-millimetric cross-section suitable for injecting at the surface of the muscles using a catheter. The project is extremely timely because the development of HMI is an emerging field with very promising expectations in the future.