MAGNetic sensing microsystem for InjectABLE magnetomyography

用于可注射肌磁描记术的磁传感微系统

• 批准号: EP/X024989/1
• 负责人: Shahid Malik
• 金额: $ 24.26万
• 依托单位: University of Glasgow
• 依托单位国家: 英国
• 项目类别: Fellowship
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FX024989%2F1
• 关键词: MAGNetic; sensing; microsystem; InjectABLE; magnetomyography

Despite several decades of research, the quest for an intuitive and physiologically appropriate human-machine interface (HMI) for the control of dexterous prostheses is far from being completed. The focus of the researchers around the world so far is on use of "Electric field" generated by the skeleton muscles for HMI. Recently, focus of the research is shifted toward measurement of "Magnetic field" generated by the ionic current flowing in muscle fiber - called as Magnetomyogram (MMG). The MMG has the potential to provide additional information about the muscle contraction with high spatial resolution since the magnetic field is not affected by the volume conductive property of tissues. The current sensing systems for MMG recording suffers from poor SNR and highly affected by the earth magnetic field and background noises in the surrounding environment. To address this, this project explores the development of a robust and highly sensitive sensing microsystem for MMG recording using magnetic sensors. It will develop a signal conditioning unit with background calibration and auto-programmable sensitivity to effectively compensate the effects of undesirable magnetic field. In addition, a proof-of-concept prototype will be demonstrated for MMG recording with a sub-millimetric cross-section suitable for injecting at the surface of the muscles using a catheter. The project is extremely timely because the development of HMI is an emerging field with very promising expectations in the future.

尽管经过几十年的研究，寻求一个直观的和生理上适当的人机界面（HMI）的灵巧假肢的控制是远远没有完成。到目前为止，世界各地研究人员的重点是使用骨骼肌肉产生的“电场”进行HMI。最近，研究的焦点转移到测量肌肉纤维中流动的离子电流所产生的“磁场”-称为磁肌图（MMG）。MMG具有提供关于具有高空间分辨率的肌肉收缩的附加信息的潜力，因为磁场不受组织的体积传导特性的影响。MMG记录的电流传感系统存在信噪比低、受地磁场和周围环境背景噪声影响大等问题。为了解决这个问题，这个项目探讨了一个强大的和高灵敏度的MMG记录使用磁传感器的传感微系统的发展。该公司将开发一个具有背景校准和自动编程灵敏度的信号调理单元，以有效地补偿不良磁场的影响。此外，还将展示一种用于MMG记录的概念验证原型，其具有亚毫米级的横截面，适合使用导管在肌肉表面注射。该项目非常及时，因为HMI的开发是一个新兴领域，未来前景非常广阔。