THE MECHANISMS OF DECREASED ADHESION AND TRANSENDOTHELIAL MIGRATION

新生儿中性粒细胞到达感染部位的时间延迟 因此，与成人中性粒细胞相比，中性粒细胞似乎 来自新生儿的能力受到损害，他们的坚持和反应 黏附介质在激活的内皮细胞上表达。 此外，新生儿的规则分离可能存在缺陷。 中性粒细胞确实会附着在刺激的内皮细胞上，因此它们 可能会被困在管腔里。

The arrival of neonatal neutrophils to the site of infection is delayed compared to adult neutrophils, therefore, it appears that neutrophils from neonates are impaired in their ability to adhere to and respond to mediators of adhesion expressed on activated endothelial cells. Additionally, there may be a defect in regulated detachment of neonatal neutrophils that do adhere to stimulated endothelial cells and thus they may remain trapped in the lumen.