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Molecular mechanism of cell adhesion and cell migration in gingival junctional epithelium.

Molecular mechanism of cell adhesion and cell migration in gingival junctional epithelium.
牙龈交界上皮细胞粘附和细胞迁移的分子机制。
批准号:
19592134
负责人:
SHIMONO Masaki
金额:
$2.25万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009

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中文摘要
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英文摘要
The aim of this study was, examine the expression of laminin γ_2, integrin β_4 and integrin α_3 in the normal and regenerating gingival junctional epithelium in order to understand the mechanism of wound healing and function of cell migration. Our results suggest that secretion of laminin γ_2 in the connective tissue may induce epithelial cell migration, and that binding of laminin γ_2 to integrin α_6β_4 and integrin α_3β_1 in the IBL may provoke cell adhesion and migration of cells facing the tooth on the enamel surface of the regenerating junctional epithelium.
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新口腔病理学
新口腔病理学
DOI: --
发表时间: 2018
期刊:
影响因子: --
作者: [Kawakami T, Kaneko K, Takaya T, Aoki S, Muraoka R, Tomida M, Okafuji N, Shoumura M, Osuga N, Nakano K, Tsujigiwa H, Nagatuka H., 長塚 仁,中野敬介]
通讯作者: 長塚 仁,中野敬介
MOLECULAR MECHANISMS OF HOMEOSTASIS AND MECHANICAL STRESS-RESPONSE IN PERIODONTAL LIGAMENT
  • 批准号:
    13470389
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $8.9万
  • 财政年份:
    2001
  • 负责人:
    SHIMONO Masaki
  • 依托单位:
Comprehensive study of root surface treatment and regeneration in periodontal disease
  • 批准号:
    10557202
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $8.06万
  • 财政年份:
    1998
  • 负责人:
    SHIMONO Masaki
  • 依托单位:
Molecular Mechanism and Signal Transduction for Salivary Secretion
  • 批准号:
    07407051
  • 项目类别:
    Grant-in-Aid for Scientific Research (A)
  • 资助金额:
    $17.98万
  • 财政年份:
    1995
  • 负责人:
    SHIMONO Masaki
  • 依托单位:
Regulatory mechanism of cell differentiation and functional manifestation in the dental pulp.
  • 批准号:
    04454455
  • 项目类别:
    Grant-in-Aid for General Scientific Research (B)
  • 资助金额:
    $4.22万
  • 财政年份:
    1992
  • 负责人:
    SHIMONO Masaki
  • 依托单位:
海外基金