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PHASE SHIFTING EFFECTS OF MELATONIN IN SIGHTED AND BLIND SUBJECTS

PHASE SHIFTING EFFECTS OF MELATONIN IN SIGHTED AND BLIND SUBJECTS
褪黑素对视力正常和失明受试者的相移作用
批准号：
3742308
负责人：
ROBERT L. SACK
金额：
$0.0万
依托单位：
OREGON HEALTH & SCIENCE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3742308
关键词：
blindness circadian rhythms drug administration rate /duration hormone regulation /control mechanism hormone therapy human subject human therapy evaluation melatonin seasonal affective disorder sleep disorders

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中文摘要
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英文摘要
The purpose of this study is to find the optimum timing, dose and duration of melatonin administration for phase advancing (shifting to an earlier time)the endogenous melatonin rhythms, which may occur in winter depression and delayed sleep phase syndrome, may lead to symptoms of insomnia, lack of energy and depression. The phase-advancing effects of melatonin may be useful for treating such disorders.
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会议论文
SLEEP PROMOTING PROPERTIES OF MELATONIN IN CIRCADIAN RHYTHM DISTURBANCES
IDENTIFICATION OF FREE-RUNNING RHYTHMS IN TOTALLY BLIND SUBJECTS
SLEEP PROMOTING PROPERTIES OF MELATONIN IN CIRCADIAN RHYTHM DISTURBANCES
STUDY OF CIRCADIAN RHYTHMS IN SHIFT WORKERS
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