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URSODEOXYCHOLATE METHOTREXATE FOR TREATMENT OF PRIMARY BILIARY CIRRHOSIS

URSODEOXYCHOLATE METHOTREXATE FOR TREATMENT OF PRIMARY BILIARY CIRRHOSIS
熊去氧胆酸甲氨蝶呤治疗原发性胆汁性肝硬化
批准号：
3742352
负责人：
KENT G BENNER
金额：
$0.0万
依托单位：
OREGON HEALTH & SCIENCE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3742352
关键词：
biliary tract disorder chemotherapy clinical trials combination chemotherapy drug screening /evaluation histology human mortality human subject human therapy evaluation liver transplantation longitudinal human study methotrexate placebos primary biliary cirrhosis ursodeoxycholate

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中文摘要
翻译
这是一个多中心，美国国立卫生研究院赞助的熊脱氧胆酸治疗试验
英文摘要
This is a multicenter, NIH-sponsored treatment trial of ursodeoxycholate (UDCA) plus methotrexate (MTX) or placebo in the treatment of primary biliary cirrhosis. Patients will be followed for six years on combined therapy. The endpoints of the study will be patient well-being, laboratory parameters, evidence of hepatic decompensation, histologic changes, need for liver transplantation, survival, and toxicity and safety.
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会议论文
URSODEOXYCHOLATE-METHOTREXATE FOR TREATMENT OF PRIMARY BILIARY CIRRHOSIS
Ursodeoxycholate-Methotrexate for Treatment of Primary Biliary Cirrhosis
NORTH AMERICAN STUDY OF TREATMENT FOR REFRACTORY ASCITES (NASTRA)
Study of sandostatin LAR in patients with cirrhosis
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