TREATMENT OF NEWLY DIAGNOSED ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN

新诊断的儿童急性淋巴细胞白血病的治疗

• 批准号: 3744062
• 负责人: KATHERINE K MATTHAY
• 金额: --
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3744062
• 关键词: acute lymphocytic leukemia; blood chemistry; bone marrow exam; child (0-11); dosage; drug administration rate /duration; human subject; human therapy evaluation; neoplasm /cancer chemotherapy; pediatric neoplasm /cancer

This study is aimed at improving the length of remission and potential for cure in this group of patients. Another purpose of this study is to define more clearly the characteristics of children within this group by laboratory studies requiring blood and bone marrow samples aimed at defining the nature of the leukemic cell. Patients will receive one of two therapies differing in the sequence, timing, and dose of the drugs given. However, the same drugs are used in both therapies. The study will compare the speed of response and duration.

这项研究旨在延长缓解时间和潜在的 以求治愈本组患者。 这项研究的另一个目的是 更清楚地定义该群体中儿童的特征 需要血液和骨髓样本的实验室研究旨在 定义白血病细胞的性质。患者将收到其中之一 两种疗法在药物顺序、时间和剂量上有所不同 给予。 然而，两种疗法使用相同的药物。 研究 将比较响应速度和持续时间。