Cord blood stem cells for cerebral palsy

脐带血干细胞治疗脑瘫

• 批准号: nhmrc : 1081516
• 负责人: A/Pr Michael Fahey
• 金额: $ 48.76万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/cord-blood-stem-cerebral-palsy/518817
• 关键词: Cord; blood; stem; cells; cerebral

Injury to the developing brain, whether sustained during pregnancy or at birth, is the underlying cause of many cognitive and motor disabilities, including cerebral palsy. This project will identify the cellular pathways that cause developmental brain injury in preterm and term infants, and then administer umbilical cord blood stem cells at different timepoints to assess their efficacy at reducing brain injury. This project will inform treatment with cord blood stem cells in high risk infants.

对发育中的大脑的损伤，无论是在怀孕期间还是在出生时，都是许多认知和运动障碍的根本原因，包括脑瘫。该项目将确定导致早产儿和足月儿发育性脑损伤的细胞途径，然后在不同时间点给予脐带血干细胞，以评估其减少脑损伤的功效。该项目将为高危婴儿的脐带血干细胞治疗提供信息。