ANDROGEN HORMONE DEFICIENCY AND REPLACEMENT IN MOTOR NEURON DISEASE

运动神经元疾病中的雄激素缺乏和替代

• 批准号: 3761444
• 负责人: JERRY R MENDELL
• 金额: --
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3761444
• 关键词: androgen receptor; degenerative motor system disease; endocrine disorder; gene mutation; hormone therapy; human subject; human therapy evaluation; muscle strength; testosterone

The muscle weakness observed in Kennedy's Disease is the direct result of the mutation of the androgen receptor gene. Aims for this study are: 1) to determine if muscle strength is altered by the androgen hormone (testosterone), to determine if muscle strength is altered by androgen hormone deficiency.

在肯尼迪病中观察到的肌肉无力是 雄激素受体基因突变的证据 本研究的目的是： 1)以确定肌肉力量是否被雄激素改变 （睾酮），以确定肌肉力量是否被雄激素改变 激素缺乏症