CRH TEST COMPARED TO ACTH AND ITT IN PATIENTS WITH ADRENOCORTICAL INSUFFICIENCY

肾上腺皮质功能不全患者中 CRH 测试与 ACTH 和 ITT 的比较

• 批准号: 3762613
• 负责人: ROBERT L. ROSENFIELD
• 金额: --
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3762613
• 关键词: adrenal disorder; adrenocorticotropic hormone; corticotropin releasing factor; diagnosis design /evaluation; diagnosis quality /standard; diagnostic tests; endocrine disorder diagnosis; human subject; insulin sensitivity /resistance

Our purpose is to compare the results of the corticotropin releasing hormone (CRH) test to the results of the ACTH and/or insulin tolerance tests in patients with various forms of adrenal insufficiency. We will test the hypothesis that the CRH test is as discriminating a measure of adrenococortical reserve as is the ACTH test in ACTH insufficient individuals and that the CRH test is as specific a measure of pituitary ACTH reserve as is the ITT.

我们的目的是比较促肾上腺皮质激素释放的结果， 促肾上腺皮质激素（CRH）试验的结果ACTH和/或胰岛素耐受性 对各种肾上腺功能不全的患者进行测试。 我们将 测试CRH测试作为区分措施的假设 肾上腺皮质储备，如ACTH试验不足 个体和CRH测试是作为具体的垂体测量 ACTH储备和ITT一样。