STEPPING OUT - Understanding the ground truth and mechanisms of falls and balance instability in community dwelling older people.

走出去——了解社区老年人跌倒和平衡不稳定的基本事实和机制。

• 批准号: EP/Y029143/1
• 负责人: Sarah Lamb
• 金额: $ 314.12万
• 依托单位: UNIVERSITY OF EXETER
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2024
• 资助国家: 英国
• 起止时间: 2024 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FY029143%2F1
• 关键词: STEPPING; OUT; Understanding; ground; truth

In Europe the costs of falls are 25 billion euros each year (2015 prices) and will rise with population ageing. Interventions to prevent falls have a small and short-lived effect and virtually no impact on serious injuries.We desperately need better solutions. Research has been held back by an inability to study falls whilst they happen in ecologically valid situations. Advances are now made possible by new, beyond state of the art facilities at the University of Exeter. The VSimulator is a 3.7m x 3.7m force plate array mounted on a motion platform with six degrees of freedom of movement allowing the creation of underfoot perturbations which have high ecological validity for falls. Coupled with integrated motion capture with or without Virtual Reality the facility generates life like scenarios including hazards during unconstrained walking (total walk distance including the force plate 15m). We will generate empirical evidence about what is happening within the balance systems to overcome or succumb to perturbations, and develop novel sensory dependency tests. We will use advanced mathematical analysis to unlock the secrets of balance control in older adults.There are 5 work programmes (WPs). WP1 will maximise knowledge about the situations in which falls commonly occur by analysing 220 falls recorded in real life situations using a crude method (inertial measurement units). This will inform the design and implementation of perturbation scenarios in later stages of the project (WP2). The centre piece is a large experiment in which 228 older people will undergo VSimulator tests (WP3). WP4 will develop analytical approaches, and WP5 will focus on the translational opportunities including new treatments and tests. The project will lay the foundation for radical improvements in fall prevention and develop the next generation of fall and balance researchers. The PI has a strong record in falls and rehabilitation research, and a distinguished leadership record.

在欧洲，跌倒的成本为每年250亿欧元（2015年价格），随着人口衰老的增长。防止跌倒的干预措施具有小而短暂的影响，几乎对严重伤害没有影响。我们迫切需要更好的解决方案。在生态有效的情况下发生的同时，无法研究研究跌倒，这是由于无法研究而阻碍了研究。现在，除了埃克塞特大学的最先进的设施之外，新的进步已经成为可能。 Vsimulator是一个37m x 37M的力板阵列，该力板安装在运动平台上，其运动自由度允许产生脚底扰动，这些脚动作对跌倒具有很高的生态有效性。加上有或没有虚拟现实的集成运动捕获，设施会产生像无限制步行期间危害的场景一样的生活（包括力板在内的总步行距离为15m）。我们将生成关于平衡系统中正在发生的事情，以克服或屈服于扰动，并开发新的感觉依赖性测试。我们将使用高级数学分析来解锁老年人平衡控制的秘密。有5个工作计划（WPS）。 WP1将通过使用粗制方法（惯性测量单元）分析在现实生活中记录的220次跌倒，从而最大程度地提高人们对跌落的情况的最大知识。这将为项目后期（WP2）的扰动方案的设计和实现提供信息。该中心部分是一个大型实验，其中228名老年人将接受Vsimulator测试（WP3）。 WP4将开发分析方法，WP5将专注于转化机会，包括新的治疗和测试。该项目将为预防秋季的根本改善奠定基础，并发展下一代的秋季和平衡研究人员。 PI在瀑布和康复研究中具有良好的记录，并具有杰出的领导记录。