DOUBLE BLIND PARALLEL GROUP COMPARISON OF LIBRAX

LIBRAX双盲平行组比较

• 批准号: 3766730
• 负责人: WILLIAM E. WHITEHEAD
• 金额: --
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3766730
• 关键词: anticholinergic agent; chlordiazepoxide; clinical trials; colon; gastrointestinal disorder chemotherapy; gastrointestinal motility /pressure; human subject; irritable bowel syndrome; muscle tone; pain; placebos; tranquilizer

The goals of the study are to determine 1) whether Librax reduces the symptoms of IBS and the motility of the distal colon more than the component drugs Clinidinium Bromide and chlordiazepoxide or placebo; and 2) whether the altered threshold for pain due to balloon distension of the bowel is caused by changes in the tone of the bowel.

该研究的目标是确定 1) Librax 是否会降低 IBS 的症状和远端结肠的蠕动比 成分药物可林溴铵和利眠宁或安慰剂；和 2）是否由于球囊膨胀而改变了疼痛阈值 肠鸣是由肠音的变化引起的。