REPRODUCTIVE AND DEVELOPMENTAL EFFECTS OF ENVIRONMENTAL TOXICANTS

尽管怀孕期间胎儿暴露一直是一个令人担忧的问题 畸形学研究和生殖流行病学，知之甚少 怀孕前接触有毒物质可能损害生育能力或大约 胎儿暴露对随后婴儿和儿童健康的影响。我们 我认为通过考虑这一连续体可以获得重要的见解 并通过职业和环境流行病学研究 在开发过程的这些阶段中的每一个阶段的暴露。我们 已经开始了一项研究计划，以解决三组 环境毒物、麻醉气体、金属和杀虫剂会影响 生育力、胎儿发育、婴儿和儿童发育。

Although fetal exposures during pregnancy have long been a concern of teratology research and reproductive epidemiology, less is known about toxic exposures before pregnancy that might impair fertility or about the effects of fetal exposures on subsequent infant and child health. We think that important insights may be gained by considering this continuum and by the epidemiologic study of occupational and environmental exposures during each of these stages in the development process. We have begun a research program to address how three groups of environmental toxicants, anesthetic gases, metals, and pesticides affect fertility, fetal development, and infant and childhood development.