CORE SUPPORT-CENTER FOR ALTERNATIVES TO ANIMAL TESTING

动物试验替代方案的核心支持中心

• 批准号: 2283015
• 负责人: JOHN M FRAZIER
• 金额: $ 8.72万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-05-01 至 1994-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2283015
• 关键词: alternatives to animals in research; drug screening /evaluation; information dissemination; tissue /cell culture; toxicant screening; toxicology

The objective of this proposal is to provide core support for the activities of the Johns Hopkins Center for Alternatives to Animal Testing (CAAT). The Center is a focus for the development of in vitro toxicity testing methodologies as well as a mechanism to communicate new developments to academia, government, industry and interested public organizations. The major activities of the Center are the Research Program, consisting of the Research Grants Program and the In Vitro Toxicology Laboratory, and the Communications/Education program. the Research Grants program supports international research aimed at developing the scientific basis for in vitro toxicity testing. The In Vitro Toxicology Laboratory, located at the Johns Hopkins School of Hygiene and Public Health, provides a unique resource for outside researchers from academia, government or industry to address research problems in in vitro toxicity testing. The Communications/Education Program provides mechanisms, including symposia, a newletter and a book series, to transfer the latest technological developments in alternative testing methodologies to the user audience. The ultimate goal of the Center is to foster the development of scientifically validated alternative methodologies which can be employed to provide the toxicological database for human risk assessment of chemical agents.

本建议的目的是为《公约》提供核心支助， 约翰霍普金斯动物试验替代中心的活动 （CAAT）。该中心是体外毒性开发的重点 测试方法以及沟通新的 学术界、政府、工业界和有关公众的发展情况 组织的该中心的主要活动是研究 计划，包括研究赠款计划和体外 毒理学实验室和通信/教育计划。的 研究赠款计划支持国际研究， 为体外毒性试验建立科学基础。的In 体外毒理学实验室，位于约翰霍普金斯大学 卫生和公共卫生，提供了一个独特的资源， 来自学术界、政府或工业界的研究人员， 体外毒性测试中的问题。通信/教育 计划提供机制，包括座谈会，一份新闻稿和一本书 系列，将最新的技术发展转移到替代产品中， 向用户受众测试方法。的最终目标 中心是培育发展科学验证 可用于提供的替代方法 用于化学剂人类风险评估的毒理学数据库。