CORE SUPPORT-CENTER FOR ALTERNATIVES TO ANIMAL TESTING

这项提议的目标是为 约翰·霍普金斯动物试验替代品中心的活动 (CAAT)。该中心是体外毒性研究的焦点 测试方法以及沟通新技术的机制 向学术界、政府、工业界和有兴趣的公众介绍最新情况 组织。该中心的主要活动是研究 计划，由研究资助计划和体外实验计划组成 毒物学实验室和通信/教育计划。这个 研究资助计划支持旨在 为体外毒性试验提供科学依据。最新消息 体外毒理学实验室，位于约翰霍普金斯大学 卫生与公共健康，为外界提供独特的资源 来自学术界、政府或行业的研究人员致力于研究 体外毒性试验中存在的问题。传播/教育 计划提供机制，包括座谈会、通讯和一本书 系列，将最新的技术发展转移到替代 向用户受众测试方法。的最终目标是 中心是培育发展的科学验证 可以采用的替代方法来提供 化学制剂人体风险评估毒理学数据库。

The objective of this proposal is to provide core support for the activities of the Johns Hopkins Center for Alternatives to Animal Testing (CAAT). The Center is a focus for the development of in vitro toxicity testing methodologies as well as a mechanism to communicate new developments to academia, government, industry and interested public organizations. The major activities of the Center are the Research Program, consisting of the Research Grants Program and the In Vitro Toxicology Laboratory, and the Communications/Education program. the Research Grants program supports international research aimed at developing the scientific basis for in vitro toxicity testing. The In Vitro Toxicology Laboratory, located at the Johns Hopkins School of Hygiene and Public Health, provides a unique resource for outside researchers from academia, government or industry to address research problems in in vitro toxicity testing. The Communications/Education Program provides mechanisms, including symposia, a newletter and a book series, to transfer the latest technological developments in alternative testing methodologies to the user audience. The ultimate goal of the Center is to foster the development of scientifically validated alternative methodologies which can be employed to provide the toxicological database for human risk assessment of chemical agents.