GROWTH HORMONE DOSE RESPONSE RELATIONSHIPS

生长激素剂量反应关系

• 批准号: 3785468
• 负责人: ROBERT DANISH
• 金额: --
• 依托单位: UNIVERSITY HOSPITALS OF CLEVELAND
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3785468
• 关键词: Turner's syndrome; child (0-11); dosage; endocrine disorder chemotherapy; genetic disorder diagnosis; human subject; skeletal disorder chemotherapy; somatotropin

The aim of this proposal is to define the growth hormone (GH) dose-response relationships in children having short stature of various causes (classical GH deficiency, normal short stature, Turner's syndrome, and unclassified short stature). The intent is to examine whether differences in GH dose responsiveness actually exist between GH deficient and GH sufficient subjects, and whether these differences could be utilized for diagnostic test purposes.

这项提案的目的是定义生长激素(GH) 不同身材矮小儿童的剂量-反应关系 病因(经典型生长激素缺乏，正常矮小，特纳综合征， 和未分类的矮小身材)。其目的是检查是否 生长激素缺乏者在生长激素剂量反应上确实存在差异 和生长激素充足的受试者，以及这些差异是否可能 用于诊断测试目的。