GROWTH HORMONE DOSE-RESPONSE RELATIONSHIPS

生长激素剂量-反应关系

• 批准号: 6246404
• 负责人: ROBERT DANISH
• 金额: $ 1.98万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-01-06 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6246404
• 关键词: Turner's syndrome; body height; child (0-11); clinical research; dosage; endocrine disorder; endocrine disorder diagnosis; hormone regulation /control mechanism; human subject; pituitary dwarfism; somatotropin

The aim of this proposal is to define the growth hormone (GH) dose- response relationships in children having short stature of various causes (classical GH deficiency, normal short stature, Turner's syndrome, and unclassified short stature). The intent is to examine whether differences in GH dose responsiveness actually exist between GH deficient and GH sufficient subjects, and whether these differences could be utilized for diagnostic test purposes. The project has been terminated. Data is being analyzed.

该提案的目的是确定生长激素（GH）剂量- 不同原因矮小儿童的反应关系 （典型的GH缺乏症，正常身材矮小，特纳综合征， 未分类的身材矮小）。目的是检验差异是否 在GH剂量反应中，GH缺乏和GH之间实际上存在剂量反应 足够的主题，以及这些差异是否可以用于 诊断测试的目的。该项目已被终止。 数据正被 分析了