GENERAL CLINICAL RESEARCH CENTER

全科临床研究中心

• 批准号: 3090048
• 负责人: DONALD F TAPLEY
• 金额: $ 189.34万
• 依托单位: COLUMBIA UNIV NEW YORK MORNINGSIDE
• 依托单位国家: 美国
• 财政年份: 1977
• 资助国家: 美国
• 起止时间: 1977-12-01 至 1995-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3090048
• 关键词: clinical trials; human subject

Continuation of the General Clinical Research Center for adult and pediatric patients at the Columbia-Presbyterian Medical Center in New York City is proposed for the purpose of providing a facility for multidisciplinary, intensive bedside clinical investigation of human disease. Support is requested for 1168 a days in the adult unit initially and 200 A days in the pediatric unit; a metabolic diet kitchen; a discrete outpatient unit with 3750 annual visits initially; a core laboratory, and a computer-based data management and analysis resource. The center is designed so that acutely ill, as well as ambulatory patients can be studied. The center provides for hospitalization of patients in a setting in which careful dietary control, skillful intensive nursing care, and precise collection of urine, stool, and blood specimens, as well as other special procedures, can be carried out. Qualified faculty members of the clinical and basic science departments of the College of Physicians and Surgeons, Columbia University will study clinical problems which embrace most of the major fields of clinical investigation. Although the primary purpose of the facility is concerned with human research, it also provides unusual opportunities for undergraduate and postgraduate training in clinical investigation. Major research activities include: Lipid and Lipoprotein metabolism; Dementias, especially Alzheimer's disease; Parkinson's Disease; Reproductive Biology; AIDS; Lead Intoxication; Infant Nutrition and Energy Expenditure; Cardiac Arrhythmias; Cardiac Transplantation; Obesity; Osteoporosis; Hyperparathyroidism; Hemolytic Anemias; Myocardial Ischemia; Psoriasis; Paget's Disease of Bone; Anorexia Nervosa; Preeclampsia; and Neuromuscular Disease.

成人和成人综合临床研究中心的延续 位于纽约的哥伦比亚长老会医疗中心的儿科患者 约克城的目的是提供一个设施， 多学科，密集的床旁临床研究， 疾病 在成人单位要求每天提供1 168美元的支助 最初和200 A天的儿科单位;代谢饮食厨房; 一个独立的门诊单位，最初每年有3750人就诊;一个核心 实验室，以及基于计算机的数据管理和分析资源。 该中心的设计，使急性病，以及走动 患者可以进行研究。 该中心提供住院治疗， 患者在一个环境中，仔细的饮食控制，熟练 加强护理，精确收集尿液、粪便和血液 标本，以及其他特殊程序，可以进行。 临床和基础科学部门的合格教师 哥伦比亚大学内科和外科医生学院的教授将研究 临床问题，包括大多数主要领域的临床 调查 尽管该设施的主要目的是 与人类研究，它也提供了不寻常的机会， 临床研究的本科生和研究生培训。 主要研究领域包括：脂质和脂蛋白代谢; 痴呆症，特别是阿尔茨海默氏病;帕金森氏病; 生殖生物学;艾滋病;铅中毒;婴儿营养和 能量消耗;心律失常;心脏移植; 肥胖;骨质疏松症;甲状旁腺功能亢进;溶血性贫血;心肌 缺血性;银屑病;佩吉特骨病;神经性厌食症; 先兆子痫和神经肌肉疾病。